Results 31 to 40 of about 509,271 (219)

Against Negativism: Why Critical Theory Should Appeal to the Good

open access: yesPolitical Philosophy
In this article, I argue against negativism in critical theory. Negativism holds that critical theory should avoid appealing to explicit positive normative standards (“the good”) in its social critique.
Luca Hemmerich
doaj   +2 more sources

Algorithms of capacity balancing of printing machineries for Alfa Foils, a.s. planning system [PDF]

open access: yesActa Montanistica Slovaca, 2009
Basic absence for orders income is not definning of rules for their evaluation. It is very important todefine necessary rules and define competence of each workers, that influence production planning, itmeans to define competence of planning workers and ...
Martin Straka, Dušan Malindžák
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Методика обеспечения функциональной устойчивости системы связи за счет выявления конфликтов

open access: yesИнформатика и автоматизация
Введение: Современные сложные технические системы часто бывают критически важными. Критичность обусловлена последствиями нарушения функционирования таких систем, не выполнением ими требуемого перечня функций и задач.
Oleg Lepeshkin   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Algorithms of capacity planning and production scheduling prognosis creation a capacity balance of Alfa Foils, a.s. planning system [PDF]

open access: yesActa Montanistica Slovaca, 2008
Firm forecasting and planning base on operative approach bears only measure of request production saturation. After overload“point of bearing” occur collapse planning system, i.e.
Zuzana Marková   +2 more
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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