Results 71 to 80 of about 3,042,978 (240)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Doing things by halves: on intermediary global institutional proposals

open access: yesEthics & Global Politics, 2016
Various cosmopolitan theorists offer global institutional prescriptions intended to be understood as residing conceptually between a system of separate domestic states and a federal world state.
Luke Ulaş
doaj   +1 more source

Parenting contracts and orders guidance [PDF]

open access: yes, 2004
First issued February 2004, Revised October ...

core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Responding to unauthorized residence: on a dilemma between ‘firewalls’ and ‘regularizations’

open access: yesComparative Migration Studies
Residence of unauthorized immigrants is a stable feature of the Global North’s liberal democracies. This article asks how liberal-democratic policymakers should respond to this phenomenon, assuming both that states have incontrovertible rights and ...
Lukas Schmid
doaj   +1 more source

A method of the organizational structure synthesis of centralized multi-agent systems with a possibility of its automatic adaptation in the event of changing the environment parameters or the set task

open access: yesИзвестия высших учебных заведений. Поволжский регион:Технические науки, 2023
Background. The object of research is multi-agent systems. The subject of the research is the methods of synthesizing the organizational structure of a multi-agent system.
Yu.V. Dubenko   +2 more
doaj   +1 more source

Homothetic interval orders [PDF]

open access: yes
N*-set, semigroup, weak order, semiorder, interval order, intransitive indifference, independence, homothetic structure ...
Bertrand Lemaire, Marc Le Menestrel
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

On Ordinal Invariants in Well Quasi Orders and Finite Antichain Orders

open access: yes, 2018
We investigate the ordinal invariants height, length, and width of well quasi orders (WQO), with particular emphasis on width, an invariant of interest for the larger class of orders with finite antichain condition (FAC).
Džamonja, Mirna   +2 more
core  

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