Evaluating statistical models for overdispersed multiomics data: a multiplex immunofluorescence case study. [PDF]
Thomas CE +12 more
europepmc +1 more source
Case‐Mix Adjustment of Multidimensional Patient‐Reported Outcomes to Assess Hospital Performance
ABSTRACT Multidimensional patient‐reported outcome measures (PROMs) are increasingly used to compare the performance of health care providers. Meaningful comparisons require the data to be adjusted for differences in case‐mix. The common approach in the literature is to aggregate PROM data into univariate summary scores prior to case‐mix adjustment. In
Nils Gutacker, Yuanyuan Gu
wiley +1 more source
Incremental value of prostate-specific antigen density beyond PI-RADS and conventional MRI features for predicting the highest ISUP grade group in patients with prostate cancer diagnosed at initial systematic prostate biopsy. [PDF]
Fan D, Niu R, Zhou F, Yang L, Zhang C.
europepmc +1 more source
ABSTRACT Background Dysphagia is a common side‐effect after radiotherapy in head and neck cancer patients. This randomized study aimed to evaluate the effect of the shaker head‐lift exercise (HLE) after 12 months with flexible endoscopic evaluation of swallowing (FEES). Methods Patients were randomly assigned to the intervention (n = 30) or the control
Signe Rödseth Smith +3 more
wiley +1 more source
ABSTRACT Background Perineural invasion (PNI) is an established adverse prognostic factor in oral squamous cell carcinoma (OSCC), but the implications of its extent as well as its relationship with surgical margin status and the extent of microscopic tumor spread remain unclear.
Michael A. Müller +7 more
wiley +1 more source
The effects of war on patients with Parkinson's disease. [PDF]
Salari M +3 more
europepmc +1 more source
Cancer‐related fatigue (CRF) is a common and debilitating symptom among colorectal cancer (CRC) patients, but its underlying biological causes remain unclear, with inflammation emerging as a leading suspect. Here, researchers analyzed inflammatory biomarkers in blood samples and evaluated responses in fatigue assessments from CRC patients at and up to ...
Anouk E. C. Bruijnzeels +3 more
wiley +1 more source
Experimentally derived biomimetic chromatographic descriptors for drug-induced phospholipidosis liability prediction. [PDF]
Stergiopoulos C, Klara V.
europepmc +1 more source
Epigenetic Markers of Cell Division and Ageing in Relation to Breast Cancer Survival
ABSTRACT Breast cancer remains a major challenge to public health. Biomarkers may be useful to improve prediction of breast cancer survival. Several epigenetic markers of cell division and ageing based on DNA methylation have been proposed. In this study, we measured these epigenetic markers in breast tumours and assessed their prognostic value.
Luca Li +10 more
wiley +1 more source
Bayesian Machine Learning for Estimating Optimal Dynamic Treatment Regimes With Ordinal Outcomes. [PDF]
Wang X, Chakraborty T, Chakraborty B.
europepmc +1 more source

