Epilepsia, EarlyView.Abstract Objective Use of neuromodulation strategies targeting thalamic nuclei, including deep brain stimulation (DBS) and responsive neurostimulation (RNS), for treatment of pediatric drug‐resistant epilepsy (DRE) is increasing, despite limited evidence for efficacy and safety. We present the initial results from the Comparative Multicenter Evaluation
Samuel A. Tenhoeve +28 more
wiley +1 more source
Classifying seizures in practice: Testing the 2025 ILAE framework among clinicians in South Africa
Epilepsia, EarlyView.Abstract Objective The 2025 International League Against Epilepsy (ILAE) seizure classification introduced a basic version for nonspecialists, but its usability is untested. We evaluated whether a multidisciplinary frontline workforce in South Africa could apply it, how consistently, and whether performance improved after self‐directed exposure ...
Aayesha J. Soni +13 more
wiley +1 more source
Penalized Cumulative Probability Model for a Continuous Outcome Subject to Detection Limits. [PDF]
Stat MedSun S, Mas VR, Archer KJ.
europepmc +1 more source
Genetic testing practices across European epilepsy centers: An ERN EpiCARE survey
Epilepsia Open, EarlyView.Abstract Objective Genetic testing plays an increasing role in the diagnostic pathway for rare and complex epilepsies. However, significant heterogeneity persists in access, implementation, and interpretation across Europe. This study aimed to assess genetic testing practices, accessibility, and challenges across expert epilepsy centers within the ...
Sébile Tchaicha +11 more
wiley +1 more source
European Eating Disorders Review, EarlyView.ABSTRACT Objective To investigate real‐world psychopharmacological prescribing patterns among Italian adolescents with anorexia nervosa (AN) compared with psychiatric controls without eating disorders, and to examine whether AN diagnosis independently predicts medication use after accounting for psychiatric comorbidities.
Marika Orlandi +5 more
wiley +1 more source
Ethical Prioritization of Healthcare Access During Pandemics in Jordan: A Cross-Sectional Study of Physician Awareness, Confidence in Ethical Decision-Making and the Role of COVID-19-Specific Training. [PDF]
J Healthc LeadershTbayshat FM +3 more
europepmc +1 more source
Validation of a stall‐side immunoglobulin assay for use in equine reproductive management
Equine Veterinary Journal, EarlyView.Abstract Background Equine foals receive IgG from mare colostrum through passive transfer. Failure of passive transfer (FPT) is a significant risk to the foal's life, leaving them vulnerable to infection and sepsis. Radial Immunodiffusion (RID) and immunoturbidimetric assays quantify IgG present in a foal sample but require a laboratory to complete ...
L. Moore +6 more
wiley +1 more source
Fatalities within seven days after equine standing sedation: A prospective, multicentre study
Equine Veterinary Journal, EarlyView.Abstract Background Information regarding mortality associated with standing procedures in horses is sparse. Objectives To report data from >12,000 standing sedations. Study Design Confidential, observational, prospective, multicentre, cohort study.
Miguel Gozalo‐Marcilla +6 more
wiley +1 more source
Statistical modeling of days alive out-of-hospital: An illustration using the SSU trial. [PDF]
J Clin Transl SciWu X +16 more
europepmc +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background CEPEF4 provides the most comprehensive contemporary dataset on perianaesthetic risk in horses. Intraoperative complications, monitoring and American Society of Anesthesiologists (ASA)‐stratified associations with death remain incompletely described.
J. I. Redondo +5 more
wiley +1 more source