Results 121 to 130 of about 282,572 (312)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Corporate Dimensions of the Securities and Futures Ordinance [PDF]
, 2003 The enactment of the Securities and Futures Ordinance, which came into effect in April 2003, marked the end of a decade-long effort to consolidate 10 ordinances regulating the securities and futures markets in Hong Kong.
Goo, SH
core
Normalized Ordinal Distance: A Performance Metric for Ordinal, Probabilistic-Ordinal, or Partial-Ordinal Classification Problems [PDF]
, 2014 In this paper, a novel application-independent performance metric for ordinal, probabilisticordinal and partial-ordinal classification problems is introduced. Conventional performance metrics for ordinal classification problems, such as mean absolute error of consecutive integer labels and ranked probability score, are difficult to interpret and may ...
openaire +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
The head of the tax office as a tax authority. Analysis of legal and tax regulations
Journal of Modern ScienceThe head of the tax office as a tax authority. Analysis of legal and tax regulations. The Tax Ordinance and other tax acts do not contain a definition of a tax authority. Article 13 of the Tax Ordinance Act lists only these authorities.
Małgorzata Chołdyńska, Piotr Waszak
doaj +1 more source
San Francisco Predictable Scheduling and Fair Treatment for Formula Retail Employees Ordinance [PDF]
, 2014 Economic and labor force changes since the Great Recession of 2007 have changed the way many American workers support themselves and their families. Today, Americans who would prefer full-time stable work are more likely to work in part-time jobs, and ...
Hong van Pham +3 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Zoning for Solar Energy: Resource Guide [PDF]
, 2015 This document is designed to help New York State localities amend zoning and other land use regulations to permit the development of solar energy systems in their jurisdictions.
Bacher, Jessica A., Nolon, John R.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source