Results 141 to 150 of about 34,296 (312)
Ordinance 124541: Immigrant and Refugee Commission Young Adult Position
Ordinance 124541, recorded as Council Bill Number 118121, authorizes a Get Engaged young adult position to the Immigrant and Refugee Commission and amends Section 3.14.545 of the Seattle Municipal ...
City Council of the City of Seattle [WA]
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zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Ordinance 10-07: Bias-Based Policing and Solicitation of Immigration Status
This Ordinance, which appears under Article IX of the Detroit, MI Code of Ordinances, specifies how city public servants can protect the safety and health of all members of the Detroit community while upholding the United States Constitution and federal ...
City Council of the City of Detroit in collaboration with other departments [MI]
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The association between county ordinances allowing off-road vehicles on public roads and crash rates
Background Legislative bodies across the country have increasingly allowed off-road vehicles (ORVs) including all-terrain vehicles (ATVs) and utility task vehicles (UTVs) on public roads, an environment for which they are not designed. In 2004, Iowa gave
Christopher D. Monson +4 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Ordinance 19-379: Immigration Detainer Compliance Emergency Amendment Act of 2012
In this Ordinance, recorded as Ordinance Number 19-379 and the Immigration Detainer Compliance Emergency Amendment Act of 2012, the Council of the District of Columbia amends policy for complying with Immigration and Customs Enforcement (ICE) detainer ...
Council of the District of Columbia [D.C.]
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Ordinance: City Services in Relation to Immigration Status
This Ordinance, which dictates that Article XXI be added to Chapter 2 of the Hartford Municipal Code, clarified that any service provided by a City of Hartford department shall be made available to residents, regardless of immigration status (unless such
Council of the City of Hartford [CT]
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