Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Treatment of a generalized scalar differential equation: analysis and explicit solution
Frontiers in PhysicsObtaining a solution of a given SDE is essential in neuroscience, especially, in modeling transmission of nerve impulses between neurons through myelin substance. This paper analyzes a particular scalar differential equation (SDE).
Laila F. Seddek +3 more
doaj +1 more source
The Information Bottleneck's Ordinary Differential Equation: First-Order Root Tracking for the Information Bottleneck. [PDF]
Entropy (Basel), 2023 Agmon S.
europepmc +1 more source
An oscillatory half-linear differential equation [PDF]
, 1997 summary:A second-order half-linear ordinary differential equation of the type $$(|y^{\prime}|^{\alpha-1}y^{\prime})^{\prime}+\alpha q(t)|y|^{\alpha-1}y=0 \leqno{{\rm (1)}}$$ is considered on an unbounded interval.
Tanigawa, Tomoyuki +2 more
core
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
, 2012 This course focuses on linear ordinary differential equations (or ODEs) and will introduce several other subclasses and their respective properties. Despite centuries of study, numerical approximation is the only practical approach to the solution of ...
Fakıoğlu, Seyfettin +1 more
core
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Behavior at infinity of psi-evanescent solutions to linear differential equations
Electronic Journal of Differential Equations, 2010 In this article we present some necessary and sufficient conditions for the existence of $psi$-evanescent solution of the nonhomogeneous linear differential equation $x'=A(t)x+f(t)$, which is related to the notion of $psi$-ordinary dichotomy for the ...
Pham Ngoc Boi
doaj