Journal of Applied MathematicsCurrently, ordinary differential equations play an important role in various fields, which is of great significance for scientific research. However, traditional inversion methods for ordinary differential equations often suffer from poor inversion bias ...
Yingping Song +4 more
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Specification testing for ordinary differential equation models with fixed design and applications to COVID-19 epidemic models. [PDF]
Comput Stat Data Anal, 2023 Liu R, Zhu L.
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Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Existence of periodic solutions for a semilinear ordinary differential equation
Electronic Journal of Differential Equations, 1998 Dancer [3] found a necessary and sufficient condition for the existence of periodic solutions to the equation $$ ddot x +g_1(dot x) + g_0(x) = f(t),.$$ His condition is based on a functional that depends on the solution to the above equation with $g_0=0$.
Petr Girg
doaj
Step-by-step comparison of ordinary differential equation and agent-based approaches to pharmacokinetic-pharmacodynamic models. [PDF]
CPT Pharmacometrics Syst Pharmacol, 2022 Truong VT +5 more
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Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Fides: Reliable trust-region optimization for parameter estimation of ordinary differential equation models. [PDF]
PLoS Comput Biol, 2022 Fröhlich F, Sorger PK.
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FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
A nonlinear sparse neural ordinary differential equation model for multiple functional processes. [PDF]
Can J Stat, 2022 Liu Y, Li L, Wang X.
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Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source