Actionable Wearables Data for the Neurology Clinic: A Proof‐of‐Concept Tool
ABSTRACT Objective Wearable devices can monitor key health and fitness domains. In multiple sclerosis (MS), monitoring step count and sleep is feasible, valid, and offers a holistic glimpse of patient functioning and worsening. However, data generated from wearables are typically unavailable at the point of care.
Nicolette Miller+12 more
wiley +1 more source
Generalized Ordinary Differential Equation Models. [PDF]
Miao H, Wu H, Xue H.
europepmc +1 more source
ABSTRACT Objective To provide a comprehensive clinical and genetic characterization of individuals with arthrogryposis multiplex congenita (AMC), focusing on the distribution of genetic etiologies across the neuromuscular spectrum and comparing myogenic and neurogenic subtypes. Methods A total of 105 individuals with AMC were clinically and genetically
Florencia Pérez‐Vidarte+13 more
wiley +1 more source
Parameter estimation and forecasting with quantified uncertainty for ordinary differential equation models using QuantDiffForecast: A MATLAB toolbox and tutorial. [PDF]
Chowell G, Bleichrodt A, Luo R.
europepmc +1 more source
Tailored parameter optimization methods for ordinary differential equation models with steady-state constraints. [PDF]
Fiedler A+4 more
europepmc +1 more source
Phenotyping Healthcare Use 2–3 Decades Before the First Multiple Sclerosis Demyelinating Event
ABSTRACT Objective Phenotype hospital, physician, and emergency department (ED) visits by diagnoses and specialty up to 29 years pre‐multiple sclerosis (MS) onset versus a matched population without MS. Methods We identified people with MS (PwMS) using population‐based administrative data from Ontario, Canada (1991–2020).
Helen Tremlett+8 more
wiley +1 more source
A Comparison of Two-Stage Approaches for Fitting Nonlinear Ordinary Differential Equation Models with Mixed Effects. [PDF]
Chow SM, Bendezú JJ, Cole PM, Ram N.
europepmc +1 more source
Genetic Profile and Symptom Pattern Explain Variability of Deep Brain Stimulation Effect in Dystonia
ABSTRACT Objective Bilateral globus pallidus pars interna deep brain stimulation (GPi‐DBS) is a recognized and effective treatment option for drug‐resistant dystonia patients. However, the clinical GPi‐DBS outcomes vary significantly. Herein, we explored the pre‐implant factors affecting GPi‐DBS effectiveness.
Mahboubeh Ahmadipour+6 more
wiley +1 more source
Customized Steady-State Constraints for Parameter Estimation in Non-Linear Ordinary Differential Equation Models. [PDF]
Rosenblatt M, Timmer J, Kaschek D.
europepmc +1 more source
Sturm comparison theorems for ordinary and partial differential equations [PDF]
J. B. Díaz, Joyce R. McLaughlin
openalex +1 more source