Results 201 to 210 of about 404,220 (323)
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner +14 more
wiley +1 more source
Parameter estimation and forecasting with quantified uncertainty for ordinary differential equation models using QuantDiffForecast: A MATLAB toolbox and tutorial. [PDF]
Chowell G, Bleichrodt A, Luo R.
europepmc +1 more source
Tailored parameter optimization methods for ordinary differential equation models with steady-state constraints. [PDF]
Fiedler A +4 more
europepmc +1 more source
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi +4 more
wiley +1 more source
A Comparison of Two-Stage Approaches for Fitting Nonlinear Ordinary Differential Equation Models with Mixed Effects. [PDF]
Chow SM, Bendezú JJ, Cole PM, Ram N.
europepmc +1 more source
Sex differences in medication discontinuation in axial spondyloarthritis.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or Janus kinase inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we ...
Rachael Stovall +9 more
wiley +1 more source
Customized Steady-State Constraints for Parameter Estimation in Non-Linear Ordinary Differential Equation Models. [PDF]
Rosenblatt M, Timmer J, Kaschek D.
europepmc +1 more source

