Results 41 to 50 of about 400,456 (327)

Constructive factorization of LPDO in two variables

open access: yes, 2005
We study conditions under which a partial differential operator of arbitrary order $n$ in two variables or ordinary linear differential operator admits a factorization with a first-order factor on the left.
A. Loewy   +8 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Transversal homoclinics in nonlinear systems of ordinary differential equations

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2000
Bifurcation of transversal homoclinics is studied for a pair of ordinary differential equations with periodic perturbations when the first unperturbed equation has a manifold of homoclinic solutions and the second unperturbed equation is vanishing.
Michal Fečkan
doaj   +1 more source

Similarity Solutions to Nonlinear Diffusion/Harry Dym Fractional Equations

open access: yesAdvances in Mathematical Physics, 2021
By using scalar similarity transformation, nonlinear model of time-fractional diffusion/Harry Dym equation is transformed to corresponding ordinary fractional differential equations, from which a travelling-wave similarity solution of time-fractional ...
Chao Yue   +3 more
doaj   +1 more source

Motion Planning of Uncertain Ordinary Differential Equation Systems [PDF]

open access: yes, 2011
This work presents a novel motion planning framework, rooted in nonlinear programming theory, that treats uncertain fully and under-actuated dynamical systems described by ordinary differential equations.
Hays, Joe   +3 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Exact Travelling-Wave Solutions of the Extended Fifth-Order Korteweg-de Vries Equation via Simple Equations Method (SEsM): The Case of Two Simple Equations

open access: yesEntropy, 2022
We apply the Simple Equations Method (SEsM) for obtaining exact travelling-wave solutions of the extended fifth-order Korteweg-de Vries (KdV) equation. We present the solution of this equation as a composite function of two functions of two independent ...
Elena V. Nikolova
doaj   +1 more source

Home - About - Disclaimer - Privacy