Results 51 to 60 of about 38,068 (262)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Method of the Logistic Function for Finding Analytical Solutions of Nonlinear Differential Equations

open access: yesМоделирование и анализ информационных систем, 2015
The method of the logistic function is presented for finding exact solutions of nonlinear differential equations. The application of the method is illustrated by using the nonlinear ordinary differential equation of the fourth order. Analytical solutions
N. A. Kudryashov
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Computational issues of solving the 1D steady gradually varied flow equation

open access: yesJournal of Hydrology and Hydromechanics, 2014
In this paper a problem of multiple solutions of steady gradually varied flow equation in the form of the ordinary differential energy equation is discussed from the viewpoint of its numerical solution.
Artichowicz Wojciech   +1 more
doaj   +1 more source

Perturbation of domain: ordinary differential equations [PDF]

open access: yesProceedings of the Royal Society of Edinburgh: Section A Mathematics, 2002
We study a boundary perturbation problem for a one-dimensional Schrödinger equation in which the potential has a regular singularity near the perturbed end point. We give the asymptotic behaviour of the eigenvalues under the perturbation. This problem arose out of the author's studies of singular elliptic operators in higher dimensions and we ...
openaire   +3 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Doubly Periodic Meromorphic Solutions of Autonomous Nonlinear Differential Equations

open access: yesМоделирование и анализ информационных систем, 2014
The problem of constructing and classifying elliptic solutions of nonlinear differential equations is studied. An effective method enabling one to find an elliptic solution of an autonomous nonlinear ordinary differential equation is described.
M. V. Demina, N. A. Kudryashov
doaj   +1 more source

On a list of ordinary differential equations problems [PDF]

open access: yesSão Paulo Journal of Mathematical Sciences, 2018
This evocative essay focuses on the mathematical activities witnessed by the author along 1962-64 at IMPA. The list of research problems proposed in September 1962 by Mauricio Peixoto at the Seminar on the Qualitative Theory of Differential Equations is pointed out as a landmark for the genesis of the research interest in the Qualitative Theory of ...
openaire   +3 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

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