Results 41 to 50 of about 392,840 (275)

Similarity Solutions to Nonlinear Diffusion/Harry Dym Fractional Equations

open access: yesAdvances in Mathematical Physics, 2021
By using scalar similarity transformation, nonlinear model of time-fractional diffusion/Harry Dym equation is transformed to corresponding ordinary fractional differential equations, from which a travelling-wave similarity solution of time-fractional ...
Chao Yue   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Constructive factorization of LPDO in two variables

open access: yes, 2005
We study conditions under which a partial differential operator of arbitrary order $n$ in two variables or ordinary linear differential operator admits a factorization with a first-order factor on the left.
A. Loewy   +8 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Transversal homoclinics in nonlinear systems of ordinary differential equations

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2000
Bifurcation of transversal homoclinics is studied for a pair of ordinary differential equations with periodic perturbations when the first unperturbed equation has a manifold of homoclinic solutions and the second unperturbed equation is vanishing.
Michal Fečkan
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Exact Travelling-Wave Solutions of the Extended Fifth-Order Korteweg-de Vries Equation via Simple Equations Method (SEsM): The Case of Two Simple Equations

open access: yesEntropy, 2022
We apply the Simple Equations Method (SEsM) for obtaining exact travelling-wave solutions of the extended fifth-order Korteweg-de Vries (KdV) equation. We present the solution of this equation as a composite function of two functions of two independent ...
Elena V. Nikolova
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Linearizability of Nonlinear Third-Order Ordinary Differential Equations by Using a Generalized Linearizing Transformation

open access: yesJournal of Applied Mathematics, 2014
We discuss the linearization problem of third-order ordinary differential equation under the generalized linearizing transformation. We identify the form of the linearizable equations and the conditions which allow the third-order ordinary differential ...
E. Thailert, S. Suksern
doaj   +1 more source

Neural ordinary differential equation control of dynamics on graphs

open access: yesPhysical Review Research, 2022
We study the ability of neural networks to calculate feedback control signals that steer trajectories of continuous-time nonlinear dynamical systems on graphs, which we represent with neural ordinary differential equations (neural ODEs).
Thomas Asikis   +2 more
doaj   +1 more source

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