Results 51 to 60 of about 400,456 (327)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Linearizability of Nonlinear Third-Order Ordinary Differential Equations by Using a Generalized Linearizing Transformation

open access: yesJournal of Applied Mathematics, 2014
We discuss the linearization problem of third-order ordinary differential equation under the generalized linearizing transformation. We identify the form of the linearizable equations and the conditions which allow the third-order ordinary differential ...
E. Thailert, S. Suksern
doaj   +1 more source

Four Steps Implicit Method for the Solution of General Second Order Ordinary Differential Equations [PDF]

open access: yes, 2009
Four steps implicit scheme for the solution of second order ordinary differential equation was derived through interpolation and collocation method. Newton polynomial approximation method was used to generate the unknown parameters in the corrector ...
Adesanya, A.O.   +3 more
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Neural ordinary differential equation control of dynamics on graphs

open access: yesPhysical Review Research, 2022
We study the ability of neural networks to calculate feedback control signals that steer trajectories of continuous-time nonlinear dynamical systems on graphs, which we represent with neural ordinary differential equations (neural ODEs).
Thomas Asikis   +2 more
doaj   +1 more source

Semilinear ordinary differential equation coupled with distributed order fractional differential equation

open access: yes, 2009
System of semilinear ordinary differential equation and fractional differential equation of distributed order is investigated and solved in a mild and classical sense.
Atanackovic, Teodor M.   +2 more
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Population Growth Models Using Fuzzy Ordinary Differential Equation

open access: yesSemina: Ciências Exatas e Tecnológicas
Fuzzy mathematics is a branch of mathematics that presents a new approach to the classical notion of set, enabling the generalization of concepts and results from classical mathematics.
Diogo Sampaio da Silva   +1 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

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