Results 121 to 130 of about 80,042 (308)
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Free integro-differential algebras and Groebner-Shirshov bases [PDF]
, 2014 The notion of commutative integro-differential algebra was introduced for the algebraic study of boundary problems for linear ordinary differential equations. Its noncommutative analog achieves a similar purpose for linear systems of such equations.
Guo, Li +5 more
core +1 more source
Protein folding with neural ordinary differential equations
Machine Learning: Science and TechnologyRecent advances in protein structure prediction, such as AlphaFold, have demonstrated the power of deep neural architectures like the Evoformer for capturing complex spatial and evolutionary constraints on protein conformation.
Arielle Sanford +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Polynomialization of ordinary differential equations given by straight-line programs [PDF]
Given a system of ordinary differential equations represented by a straight-line program, we show how to compute an equivalent ordinary differential system represented by a straight-line program which only uses ring operations.
van der Hoeven, Joris +2 more
core +2 more sources
On bounded solutions of differential systems
Вестник КазНУ. Серия математика, механика, информатика, 2022 The question of the existence of bounded solutions on an infinite interval of a linear inhomogeneous system of ordinary differential equations in a finite-dimensional space is considered. The study of bounded solutions of systems of ordinary differential
T. M. Aldibekov
doaj
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Results in PhysicsThis study addresses the solution of differential equations converted into stochastic differential equations with the introduction of a noise term. To simplify the stochastic complexity, we employ a transformation, converting the equations into ordinary ...
Jamil Abbas Haider +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source