Results 101 to 110 of about 80,042 (308)
One step multiderivative methods for first order ordinary differential equations [PDF]
, 1981 A family of one-step multiderivative methods based on Padé approximants to the exponential function is developed. The methods are extrapolated and analysed for use in PECE mode.
E. H. Twizell +3 more
core +1 more source
Cauchy-Kowalevski and polynomial ordinary differential equations
Electronic Journal of Differential Equations, 2012 The Cauchy-Kowalevski Theorem is the foremost result guaranteeing existence and uniqueness of local solutions for analytic quasilinear partial differential equations with Cauchy initial data. The techniques of Cauchy-Kowalevski may also be applied to
Roger J. Thelwell +2 more
doaj
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Spatio-temporal numerical modelling of whooping cough dynamics [PDF]
, 2001 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The SIR (Susceptible/Infectious/Recovered) whooping cough model involving nonlinear ordinary differential equations is studied and extended to incorporate (
Piyawong, Wirawan
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
G and Gamma Convergence for Ordinary Differential Equations [PDF]
, 1977 The notes cover some main ideas in the theory of G convergence for ordinary differential equations, discussing the problem of non uniqueness of solutions to Cauchy problem (Peano phaenomenon).
PICCININI, Livio Clemente
core
Converting DAE models to ODE models: application to reactive Rayleigh distillation [PDF]
, 2013 This paper illustrates the application of an index reduction method to some differential algebraic equations (DAE) modelling the reactive Rayleigh distillation.
Monfreda, Fabien +3 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
On Lipschitz conditions for ordinary differential equations in Fréchet spaces [PDF]
, 1998 summary:We will give an existence and uniqueness theorem for ordinary differential equations in Fréchet spaces using Lipschitz conditions formulated with a generalized distance and row-finite ...
Herzog, Gerd
core +1 more source