Results 91 to 100 of about 94,059 (356)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Cauchy-Kowalevski and polynomial ordinary differential equations
Electronic Journal of Differential Equations, 2012 The Cauchy-Kowalevski Theorem is the foremost result guaranteeing existence and uniqueness of local solutions for analytic quasilinear partial differential equations with Cauchy initial data. The techniques of Cauchy-Kowalevski may also be applied to
Roger J. Thelwell +2 more
doaj
Extrapolation methods for first order ordinary differential equations
, 1980 Given a system of fist order differential equations, whose coefficient matrix has constant elements, with initial conditions specified, a family of extrapolating algorithms based on Pade approximants to the exponential function is developped.
Twizell, E H
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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
A family of difference schemes for fourth order parabolic partial differential equations
, 1983 A family of methods is developed for the numerical solution of fourth order parabolic partial differential equations in one- and two-space variables.
Khaliq, AQM, Twizell, EH
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Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Backward difference replacements of the space derivative in first order hyperbolic equations
, 1983 Two families of two-time level difference schemes are developed for the numerical solution of first order hyperbolic partial differential equations with one space variable.
Khaliq, AQM, Twizell, EH
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Converting DAE models to ODE models: application to reactive Rayleigh distillation [PDF]
, 2013 This paper illustrates the application of an index reduction method to some differential algebraic equations (DAE) modelling the reactive Rayleigh distillation.
Monfreda, Fabien +3 more
core +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Finite-difference solutions of tenth-order boundary-value problems
, 1994 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.In this thesis finite difference methods are used to obtain numerical solutions for a class of high-order ordinary differential equations with applications ...
Siddiqui, Aijaz Ahmad
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