Results 51 to 60 of about 53,436 (301)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PYTHON IN ORDINARY DIFFERENTIAL EQUATIONS LEARNING

open access: yesBarekeng
Using software in mathematics learning can improve students' soft and hard mathematics skills at the high school and college levels. Therefore, using software in the learning process is important, including in learning Differential Equations.
Sigit Sugiarto   +2 more
doaj   +1 more source

Oscillatory bifurcation for semilinear ordinary differential equations

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2016
We consider the nonlinear eigenvalue problem \[u''(t) + \lambda f(u(t)) = 0, \quad u(t) > 0, \quad t \in I := (-1,1), \quad u(1) = u(-1) = 0, \] where $f(u) = u + (1/2)\sin^k u$ ($k \ge 2$) and $\lambda > 0$ is a bifurcation parameter.
Tetsutaro Shibata
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Green's Function Method for Ordinary Differential Equations

open access: yesمجلة المختار للعلوم, 2013
The analytical solution of non homogeneous boundary value problem in the form: Lyx=fx          axb                              B1ya=0                               B2yb=0 are obtained by using Green's function method.
Fouad A Zein Elarab   +1 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Time averaging for ordinary differential equations and retarded functional differential equations

open access: yesElectronic Journal of Differential Equations, 2010
We prove averaging theorems for non-autonomous ordinary differential equations and retarded functional differential equations in the case where the vector fields are continuous in the spatial variable uniformly with respect to the time and the ...
Mustapha Lakrib, Tewfik Sari
doaj  

From MIN model to ordinary differential equations

open access: yesJournal of Integrative Bioinformatics, 2007
Biological interaction networks can be modeled using the Modular Interaction Network (MIN) formalism, which provides an intermediary modeling level between the biological and mathematical ones.
Yartseva A.   +3 more
doaj   +1 more source

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