Results 61 to 70 of about 80,042 (308)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Backward difference replacements of the space derivative in first order hyperbolic equations [PDF]

open access: yes, 1983
Two families of two-time level difference schemes are developed for the numerical solution of first order hyperbolic partial differential equations with one space variable.
Khaliq, AQM, Twizell, EH
core  

Computing with polynomial ordinary differential equations

open access: yesJournal of Complexity, 2016
In 1941, Claude Shannon introduced the General Purpose Analog Computer(GPAC) as a mathematical model of Differential Analysers, that is to say as a model of continuous-time analog (mechanical, and later one electronic) machines of that time. Following Shannon's arguments, functions generated by GPACs must be differentially algebraic.
Bournez, Olivier   +2 more
openaire   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Finite-difference solutions of tenth-order boundary-value problems [PDF]

open access: yes, 1994
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.In this thesis finite difference methods are used to obtain numerical solutions for a class of high-order ordinary differential equations with applications ...
Siddiqui, Aijaz Ahmad
core  

PYTHON IN ORDINARY DIFFERENTIAL EQUATIONS LEARNING

open access: yesBarekeng
Using software in mathematics learning can improve students' soft and hard mathematics skills at the high school and college levels. Therefore, using software in the learning process is important, including in learning Differential Equations.
Sigit Sugiarto   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Numerical solution of nonlinear boundary value problems for ordinary differential equations in the continuous framework [PDF]

open access: yes, 2013
Ordinary differential equations (ODEs) play an important role in mathematics. Although intrinsically, the setting for describing ODEs is the continuous framework, where differential operators are considered as maps from one function space to another ...
Birkisson, Asgeir
core   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Time averaging for ordinary differential equations and retarded functional differential equations

open access: yesElectronic Journal of Differential Equations, 2010
We prove averaging theorems for non-autonomous ordinary differential equations and retarded functional differential equations in the case where the vector fields are continuous in the spatial variable uniformly with respect to the time and the ...
Mustapha Lakrib, Tewfik Sari
doaj  

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