Results 61 to 70 of about 53,436 (301)

Evanescent solutions for linear ordinary differential equations

Electronic Journal of Qualitative Theory of Differential Equations, 2002
The problem of existence of the solutions for ordinary differential equations vanishing at $\pm \infty $ is considered.
C. Avramescu
doaj   +1 more source

Numerical Solution of Stieltjes Differential Equations

Mathematics, 2020
This work is devoted to the obtaining of a new numerical scheme based on quadrature formulae for the Lebesgue–Stieltjes integral for the approximation of Stieltjes ordinary differential equations.
Francisco J. Fernández, F. Adrián F. Tojo   +1 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

On Geometric-Analytic Aspects of Solvable Nonlinear Ordinary Differential Equations and Some Applications

Mathematics
A geometric-analytic approach to studying invariants of solvable nonlinear ordinary differential equations is developed. In particular, there is described in detail a general scheme of constructing solvable nonlinear ordinary differential equations ...
Anatolij K. Prykarpatski, Victor A. Bovdi, Petro Y. Pukach, Yarema A. Prykarpatsky, Myroslava I. Vovk   +4 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Geometric Linearization of Ordinary Differential Equations

Symmetry, Integrability and Geometry: Methods and Applications, 2007
The linearizability of differential equations was first considered by Lie for scalar second order semi-linear ordinary differential equations. Since then there has been considerable work done on the algebraic classification of linearizable equations and ...
Asghar Qadir
doaj  

Averaging methods for piecewise-smooth ordinary differential equations

AIMS Mathematics, 2019
The averaging method is developed for periodic piecewise-smooth systems. We discuss the behavior of solutions intersecting the discontinuity boundary and the problems it introduces. We illustrate these difficulties on specific examples.
Michal Fečkan, Július Pačuta, Michal Pospíśil, Pavol Vidlička   +3 more
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Doubly Periodic Meromorphic Solutions of Autonomous Nonlinear Differential Equations

Моделирование и анализ информационных систем, 2014
The problem of constructing and classifying elliptic solutions of nonlinear differential equations is studied. An effective method enabling one to find an elliptic solution of an autonomous nonlinear ordinary differential equation is described.
M. V. Demina, N. A. Kudryashov
doaj   +1 more source