Results 131 to 140 of about 1,781 (243)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Step average linear differential inclusions of variable dimension

, 2017
Теория дифференциальных включений начала свое развитие в начале тридцатых годов 20-го века с публикаций А. Маршо и С. Заремба. Однако бурное развитие данной теории началось с 60-х годов прошлого века благодаря работам Т. Важевского и А.Ф.
Кичмаренко, Ольга Дмитриевна, Плотнiков, А. А., Плотников, А. А., Plotnikov, A. A., Кічмаренко, Ольга Дмитрівна, Kichmarenko, Olha D.   +5 more
core  

Mapping cellular vulnerability in Parkinson's disease using retro-AAVs and preformed α-synuclein fibrils. [PDF]

Transl Neurodegener
Geibl FF, Musa AAS, Dietrich L, Wolter H, Wokosin DL, Khudayberdiev S, Rust MB, Chen R, Dawson VL, Dawson TM, Oertel WH, Surmeier DJ, Henrich MT.   +12 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Protein fingerprints of brain-derived extracellular vesicles predict types of tau pathology. [PDF]

Alzheimers Res Ther
Espourteille J, Barve A, Zufferey V, Leroux E, Perbet R, Bégard S, Caillierez R, Maurage CA, Toni N, Buée L, Colin M, Richetin K.   +11 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Sur les équations et inclusions différentielles : existence et approximation asymptotique de solutions

, 2016
In the first part of this thesis, we present, discuss and comment some results from works on existence of solutions and extremal solutions for some differential and integral equations.The second part is devoted to the presentation and the justification ...
Bourada, Amel
core  

Tau from SPAM Transgenic Mice Exhibit Potent Strain-Specific Prion-Like Seeding Properties Characteristic of Human Neurodegenerative Diseases. [PDF]

Neuromolecular Med
Smith ED, Paterno G, Bell BM, Gorion KM, Prokop S, Giasson BI.   +5 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Simple analytical solutions for the optical properties of multilayered confocal prolate spheroids in the quasistatic approximation. [PDF]

Discov Nano
Ali M, Huang F.
europepmc   +1 more source