Results 161 to 170 of about 3,808,046 (284)

Ordinary general meeting of shareholders

, 1995
Consiglio Nazionale delle Ricerche (CNR).
Banca d'Italia, Rome (Italy)
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Engineered probiotics platform for resolvin E1 biosynthesis confers protection against inflammatory disease. [PDF]

Clin Transl Med
Li X, Lin J, Liu Q, Wu Y, Wu Q, Zhao Z, Cai Y, Lin S, Zheng Z, Chen X, Li J, Yang Z.   +11 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

APOBEC3-driven attenuation of the 2022 global outbreak monkeypox virus relative to its clade IIb ancestor. [PDF]

Nat Commun
Sumner RP, Eke L, Hernáez B, Hood AJM, Sancheira Freitas T, Ashby H, Ellis A, Petit M, Lant S, Stokes I, Parija P, Alonso I, Alvarez-de Miranda FJ, Unanue AR, Maringer K, Dietrich I, Charleston B, Smith GL, Ulaeto DO, Alcamí A, Maluquer de Motes C.   +20 more
europepmc   +1 more source

First order systems of ordinary differential equations having a given four-dimensional Lie group as their symmetry group

We determine systems of the first order ordinary differential equations such that their group of symmetries contains the four-dimensional filiform Lie subgroup.
Maingi, Stephen Wachira
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

RICTOR Prevents Decidualization Disorder in Women With Advanced Maternal Age via Regulating FoxO1 Nuclear Export. [PDF]

Aging Cell
Lin Y, Sun J, Ying Y, Li D, Ying Y, Shen X, Sun X, Zhang D, Wu Y, Zhang R.   +9 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Single-cell transcriptomics reveals distinct microglial state remodeling associated with the (R)-nicotine/diosmetin combination and galantamine in LPS-challenged BV2 cells. [PDF]

Front Immunol
Liu Y, Yu H, Zhang J, Li X, Ma Y, Guang C, Mu W, Chen H, Hou H.   +8 more
europepmc   +1 more source