Results 191 to 200 of about 3,808,046 (284)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

A modified model of cardiac reverse remodeling following abdominal aortic banding and debanding in rats. [PDF]

J Hypertens
He S, Zhang Y, Shi J, Jiang J, Liu T, Deng W, Li W, Bai Y, Qiu J, Li Y, Jin Q, Chowienczyk P, Zhang L, Xie M, Gu H, Wang J.   +15 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Effects of Dietary Sterol-Rich Yeast Hydrolysate on Serum Lipid Indices, Intestinal Morphology, Digestive Enzyme Activities, Barrier-Related Gene Expression, and Cecal Microbiota in Yellow-Feathered Broiler Breeder Hens. [PDF]

Animals (Basel)
Zhang Y, Shi Z, Li M, Si H, Fan B, Li X, Li Y, Wang X, Liu J, Xi L.   +9 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Fetal sex shapes maternal immune adaptation: placental extracellular vesicles differentially reprogram the phenotype, metabolism, and function of circulating monocytes. [PDF]

Front Immunol
Avalos J, Sabbione F, Rios D, Grasso DH, Garcia MN, Aguilera F, Merech F, Aiello H, Meller C, Ramhorst R, Hauk V, Gori S, Leirós CP, Vota DM, Paparini DE.   +14 more
europepmc   +1 more source

Targeting macrophage glycogen metabolism attenuates ulcerative colitis by suppressing IL-1β production through UDPG-P2Y₁₄ signaling. [PDF]

Mol Med
Tong S, Zhu T, Liang S, Cui Y, Ma Y, Zhang X, Bian Y, Wei K, Wu S, Ma J.   +9 more
europepmc   +1 more source

On the transformation theory of ordinary second-order linear symmetric differential expressions [PDF]

Czechoslovak Mathematical Journal, 1982
openaire   +2 more sources

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

TLR7 Inhibition Limits Ischemic Cardiac Injury by Disrupting ITGAM-Dependent Immune-Endothelial Interactions. [PDF]

JACC Basic Transl Sci
Li Y, Yang Y, Park C, Ren B, Li R, Shetty A, Williams B, Li Z, Zou L, Chao W.   +9 more
europepmc   +1 more source