Results 51 to 60 of about 996,087 (297)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A Nonmonotonic Sequent Calculus for Inferentialist Expressivists [PDF]

open access: yes, 2016
I am presenting a sequent calculus that extends a nonmonotonic consequence relation over an atomic language to a logically complex language. The system is in line with two guiding philosophical ideas: (i) logical inferentialism and (ii) logical ...
Hlobil, Ulf
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Gabriel Josipovici et la fabrique de l’ordinaire

open access: yesRevue LISA, 2014
This paper focuses on the idea of the ordinary in the works of Gabriel Josipovici. It argues that the ordinary in Josipovici’s works is not only a theme, but is part and parcel of the writer’s novelistic strategies, characterising both language and ...
Marcin Stawiarski
doaj   +1 more source

Gender Differences in the Language of Mathematics in Secondary Schools

open access: yesInternational Journal of Trends in Mathematics Education Research, 2020
This study investigated gender difference in students’ understanding of the language of mathematics at ordinary secondary school level in Tanzania. The participants were 489 students from 8 ordinary secondary schools.
Makungu Bulayi
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Exploring ‘unknown worlds’: The lives and careers of non-native speaking teachers of English in Asia [PDF]

open access: yes, 2007
It is a decade since Richards remarked that “How the teacher believes, thinks, acts and reacts is central to educational endeavour, but about the EFL (English as a foreign language) language teacher we know almost nothing” (1997:243), going on to suggest
Hayes, David
core  

Equivariant cohomology over Lie groupoids and Lie-Rinehart algebras [PDF]

open access: yes, 2009
Using the language and terminology of relative homological algebra, in particular that of derived functors, we introduce equivariant cohomology over a general Lie-Rinehart algebra and equivariant de Rham cohomology over a locally trivial Lie groupoid in ...
A. Dold   +33 more
core   +3 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

A Non-mediational Approach to Emotions and Feelings

open access: yesFrontiers in Psychology, 2019
The present analysis proposes a non-mediational approach to the study of affective phenomena. It starts off with the common recognition that “emotion” is not a technical term. Even so, researchers often treat it as if it were, confusing ordinary language
Ricardo Pérez-Almonacid   +1 more
doaj   +1 more source

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