Results 201 to 210 of about 528,470 (339)

Policy Spandrels: How Design Decisions Can Open Up Spaces for Unintended Policy Change

European Policy Analysis, EarlyView.
ABSTRACT This article introduces the concept of policy spandrels to make sense of public policies producing second‐order effects that are unintentional from the perspective of policy design and yet are fraught with consequences. By analogy with architectural spandrels—leftover spaces that can be used for unforeseen purposes—policy change can be enabled
Martino Maggetti
wiley   +1 more source

Impact mechanisms of grandparental care on social isolation among older migrants: evidence from a megacity in China. [PDF]

BMC Geriatr
Li X, Han J, Wang Y, Zhang C.
europepmc   +1 more source

Preclinical signal for a disease‐modifying effect on seizure cluster severity with intermittent diazepam treatment

Epilepsia, EarlyView.
Abstract Objective In epilepsy, daily treatment provides only symptomatic seizure control, leaving a significant unmet need for a treatment that affects the underlying predisposition to seizures. Here, in a first‐of‐its‐kind study, we test the hypothesis that intermittent treatment of seizure clusters with diazepam in the kainic acid post‐status ...
Qian Wu, Michelle Guignet, Jonathan Vuong, H. Steve White, Wesley T. Kerr, Evelyn K. Shih, Leock Y. Ngo, Enrique Carrazana, Adrian L. Rabinowicz   +8 more
wiley   +1 more source

A Critical Consideration of Two Methodologies of General Jurisprudence. [PDF]

Oxf J Leg Stud
Cortés-Monroy J.
europepmc   +1 more source

Continuous outcome estimation in N‐of‐1 trials for accelerated decision‐making

Epilepsia, EarlyView.
Abstract Objective N‐of‐1 trials aim to determine the therapeutic effect for a single individual. This individualized approach necessitates collecting multiple data points over time through repeated alternating periods of active treatment and a comparator or control condition.
Victoria Defelippe, František Bartoš, Eric‐Jan Wagenmakers, Kees P. J. Braun, Floor E. Jansen, Willem M. Otte   +5 more
wiley   +1 more source

Language and labels from the lab: Definitions in the stem cell-based embryo model debate. [PDF]

Stem Cell Reports
M'hamdi HI.
europepmc   +1 more source

Assessment of Maladaptive Exercise History Among Individuals With Eating Disorders: Validation of a Brief, Self‐Report Measure

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Maladaptive exercise is a common symptom of eating disorders (EDs). While several measures exist to assess current maladaptive exercise, there are no validated self‐report tools to assess maladaptive exercise history—an important symptom domain among individuals with lifetime EDs.
Katherine Schaumberg, Hunna J. Watson, Laura M. Thornton, Hannah L. Kennedy, Shu H. Ong, Preston Roche, Kayla Costello, Wesley R. Barnhart, Sian B. Pauley‐Gadd, Rachael E. Flatt, Andreas Birgegård, Lisa Dinkler, Afrouz Abbaspour, Emma Forsén Mantilla, Elin Monell, Emma M. Frans, Sarah Barakat, Michaela A. Pettie, Richard Parker, Sarah Maguire, Jennifer Jordan, Martin A. Kennedy, Nailah Adams Morancie, Cynthia M. Bulik   +23 more
wiley   +1 more source

Illusionism, Moore, and Chalmers. [PDF]

Front Psychol
Loginov EV.
europepmc   +1 more source

Stanley Cavell [PDF]

, 2003
Eldridge, Richard Thomas
core   +2 more sources

When Rare Is Not Small: Amyotrophic Lateral Sclerosis Initiatives and Therapy

Exploration, EarlyView.
In the precision‐medicine era, rare diseases must not be sidelined in translational infrastructure. The Mr. Cai Lei—led “Ice‐Breaking Team” turns an amyotrophic lateral sclerosis patient community into a sustainable ecosystem, realigning philanthropy, data, and research and development to reshape rare‐disease pipelines and guide precision therapies ...
Yang Liu, Xue Xia, Yingfang Chen, Haoying Yang, Xiaochen Chen, Lei Cai, Bingyang Shi   +6 more
wiley   +1 more source