Results 71 to 80 of about 372,548 (312)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Ordained Married Women in Tang China: Two Case Studies

Religions
Historical records and tomb inscriptions have provided foundational insights into the lives of elite women in the Tang Dynasty. However, our understanding of their beliefs—particularly their modes of participation and how they negotiated the tensions ...
Wei Wu, Mianheng Liu
doaj   +1 more source

Ordination by detrended correspondence analysis (DCA) of the vegetation of Swartboschkloof, Jonkershoek, Cape Province

Bothalia: African Biodiversity & Conservation, 1987
The data of a Braun-Blanquet vegetation classification was ordinated using detrended correspondence analysis (DCA). This was done at the Fynbos Biome intensive study site, Swartboschkloof, Jonkershoek, to investigate the factors determining the ...
D. J. Mcdonald
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Innovation and Competition: The Role of Finance Constraints in a Duopoly Case. [PDF]

In this paper we analyse the role of financial resources in a process of competition interpreted as a continuous restructuring of productive capacities. Financial constraints appear an essential means of co-ordination.
Amendola, Mario, Gaffard, Jean-Luc, Musso, Patrick   +2 more
core  

Integration and continuity of primary care: polyclinics and alternatives - a patient-centred analysis of how organisation constrains care co-ordination [PDF]

, 2015
Background An ageing population, the increasing specialisation of clinical services and diverse health-care provider ownership make the co-ordination and continuity of complex care increasingly problematic.
Abbott, Adamson, Addicott, Ahgren, Ahgren, Alexander, Alexander, Alexander, Alexander, Alexander, Alkema, Allen, Allen, Allen, Alyahya, Andersson, Anell, Antunes, Archer, Aronson, Arora, Austin, Avery, Bacharach, Badamgarav, Baeza, Baicker, Baker, Baker, Banks, Bardsley, Bartlett, Barton, Basu, Battersby, Baxter, Baxter, Beaulieu, Bergeron, Berliner, Berridge, Bevan, Bhaskar, Bihan, Bindman, Bindman, Bitektine, Blendon, Boaden, Bode, Bodenheimer, Bodenheimer, Borgermans, Bower, Boyle, Braithwaite, Brandsen, Breslau, Briscoe, Brommels, Brown, Burns, Byng, Byng, Calltorp, Campbell, Campbell, Chambers, Chambers, Charles-Jones, Checkland, Chen, Christiana, Coast, Coleman, Coleman, Collins, Cooper, Cooper, Cornwell, Courpasson, Craig, Craske, Crooks, Cunningham, Currie, Darzi, Darzi, Davies, Davies, De Bruin, De Maeseneer, Department for Communities and Local Government, Department of Health, Department of Health (DoH), Department of Health and Social Security (DHSS), Dietrich, Dixon, Donahue, Ekman, Elston, Enthoven, Errasti, Ershova, Esterman, Ettlinger, Evans, Feachem, Feiock, Fennell, Ferlie, Ferlie, Ferlie, Finch, Firestone, Fisher, Forbes, Forbes, Fortney, Freeman, Freeman, Friedberg, Fuller, Gilbody, Gittell, Gittell, Glendinning, Glied, Goodwin, Grant, Gravelle, Gray, Gridley, Grielen, Gröne, Guillebaud, Gulbrandsen, Guthrie, Guthrie, Haggerty, Hallam, Ham, Hanlon, Hansson, Hansson, Harrison, Healthcare for London, Heenan, Heje, Hellinger, Hesselink, Higson, Hjortdahl, Hjortdahl, Hofmarcher, Hollander, Howe, Huntley, Hutt, Hvidman, Iglehart, Imison, Johansen, Kai, Kane, Kane, Kearley, Kennedy, Kirchner, Kodner, Kodner, Kringos, Lahr, Lamont, Lang, Lanier, Leichsenring, Leichsenring, Leutz, Lewis, Lister, Lo Scalzo, Locke, London Health Planning Consortium, Luppa, Lyratzopoulos, MacAdam, Mandell, Marshall, Matscheck, Mayo-Bruinsma, McCallum, McNulty, McPherson, Mercer, Mercer, Ministry of Health, Mintzberg, Mintzberg, Mohr, Mohr, Mojtabai, Morales-Asencio, Morecroft, Mur-Veeman, National Audit Office, Nolte, Nutting, O’Dowd, Pawson, Peckham, Popper, Powell Davies, Powell Davies, Praktikertjänst, Pratt, Preen, Priebe, Provan, Provan, Provan, RAND Europe, Reeves, Rehnberg, Reid, Reilly, Robinson, Roemer, Roland, Rose, Ross, Russell, Russell, Safran, Saltman, Sans-Corrales, Sareen, Sareen, Sargent, Sari, Saultz, Schers, Schillinger, Schoen, Scott, Shaoul, Sheaff, Sheaff, Sheaff, Sheaff, Sheaff, Sheaff, Sheaff, Shortell, Sibbald, Smith, Snelgrove, Southon, Stavrou, Steel, Sullivan, Swedish Association of Local Authorities and Regions, Sylvain, Talbot-Smith, Tarrant, Thompson, Tickle, Timmermans, Tudor-Hart, Turner, Vega, Venning, von Bültzingslöwen, Wagner, Watkins, Weingarten, Westrin, Williamson, Wilson, Wilson, Winstone, Wong, Woodward, Øvretveit, Øvretveit, Øvretveit, Øvretveit, Øvretveit, Øvretveit, Øvretveit, Øvretveit, Øvretveit   +291 more
core   +2 more sources

ALL ORDINALS ARE COP-ROBBER ORDINALS

The game of cops and robbers, played on a fixed graph $G$, is a two-player game, where the cop and the robber (the players) take turns in moving to adjacent vertices. The game finishes if the cop lands on the robber's vertex. In that case we say that the cop wins. If the cop can always win, regardless of the starting positions, we say that $G$ is a cop-
Chapital, Jorge Cruz, Flídr, Tomáš, Ivan, Maria-Romina   +2 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Analysis of the diversity of STR-loci in the samples of bulls of Red Scandinavian and Holstein breeds

Аграрная наука Евро-Северо-Востока
Standardized indicators of α- and β-diversity (𝒚′𝒌𝒎) calculated by DNA microsatellites (STR) in samples of bulls of Red Scandinavian (RED, n = 29) and Holstein (HOL, n = 45) breeds (each with three sub-samples) were analyzed using one-two- and ...
V. M. Kuznetsov
doaj   +1 more source