Results 81 to 90 of about 106,872 (249)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

The problems of the the Co-Ordination problem. [PDF]

open access: yes
This paper is focused on the Hayekian understanding of the operation of the market as the continuous solution of a co-ordination problem in a decentralised decision-making system.
Miguel A. Durán
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Women's Ordination: Why Not!?

open access: yes, 2015
<p>The issue of ordination of women to ministry has been the cause of fierce debate within many Christian communions. For instance, the Anglican Church has struggled to come to terms with the issue, accepting female ordinands in some regions, but ...
Roennfeldt, Ray C.
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Should Ordination Be Considered a Sacrament in the Seventh-day Adventist Church? An Evaluation in the Light of the Biblical Data

open access: yes, 2015
While Catholic theology places importance on the sacramental nature of ordination, Protestants have generally rejected the idea. This paper examines whether a biblical case can be made for ordination to be considered a sacrament.
Jackson, Wendy
core   +1 more source

Ar trebui femeile să fie hirotonite ca pastori? Considerații asupra Vechiului Testament – partea I

open access: yesTheoRhēma, 2013
In the modern discussion over whether women should be ordained as pastors, the foundational passage for both those who affirm and those who oppose women’s ordination is Gen 1–3. Those who affirm women’s ordination find in the Genesis creation accounts a
Richard M. Davidson
doaj  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Women, Leadership, and Ordination in the Anglican Church in Nigeria

open access: yesAfrican Christian Theology
Paul’s injunction in 1 Corinthians 14:26-40 has often been used to restrict women from holding certain leadership positions in the Church. This paper examines 1 Corinthians 14:26-40 in light of the female ordination debate in the Anglican Church in ...
Mercy Uwaezuoke CHUKWUEDO
doaj   +1 more source

A voice from the margins: Investigating the African Adventist rationale on the quest for female ordination

open access: yesVerbum et Ecclesia, 2016
Discussions surrounding women s ordination reached a peak with the 60th General Conference Session (GCS 2015) of the Seventh-day Adventist (SDA) Church. A report compiled by a section of delegates from the East-Central Africa Division Biblical Research
Rebecca J. Lagat
doaj   +1 more source

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