Results 81 to 90 of about 55,849 (252)
Advances in Mathematics, 1997 Let $j$ be an elementary embedding of $V_λ$ into $V_λ$ that is not the identity, and let $κ$ be the critical point of $j$. Let $\Cal A$ be the closure of $\{j\}$ under the operation $a (b)$ of application, and let $Ω$ be the closure of $\{κ\}$ under the operation $\min \{ξ: a(ξ) \ge b(α)\}$.
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Plant and Fungal Systematics, 2019 Pluteus fenzlii is a rare Eurasian lignicolous fungus, an iconic bright yellow species that attracts attention. Its habitat in the Białowieża Virgin Forest, Poland, is dominated by Carpinus betulus with admixture of Quercus robur, Tilia cordata and Picea
Tomáš Kučera +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Qualitative Ordinal Scales: The Concept of Ordinal Range
Quality Engineering, 2004 Many practical problems of quality control involve the use of ordinal scales. Questionnaires planned to collect judgments on qualitative or linguistic scales, whose levels are terms such as ‘‘good,’’ ‘‘bad,’’ ‘‘medium,’’ etc., are extensively used both in evaluating service quality and in visual controls for manufacturing industry.
FRANCESCHINI, FIORENZO +2 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Macroeconomic co-ordination as an economic policy concept - opportunities and obstacles in the EMU [PDF]
This paper traces the euro zone’s inadequate macroeconomic performance in recent years back to the predominance of a restrictive macroeconomic policy mix based on a ‘new monetarist’ approach to economic policy.
Achim Truger, Eckhard Hein
core +4 more sources
Revista Mexicana de Biodiversidad, 2011 The geographic distribution of the species of Datura in Mexico was analyzed using numerical analysis of natural populations documented by herbarium specimens.
Mario Luna-Cavazos, Robert Bye
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source