Case Report: Evolution of a BRAF V600E-mutant papillary thyroid carcinoma from latissimus dorsi metastasis and squamous transformation to PD-L1 upregulation and effective immunotherapy [PDF]
Frontiers in ImmunologyThis case report describes an unusual clinical course of a patient with papillary thyroid carcinoma (PTC). The patient sequentially developed metastases to the cervical lymph nodes, lungs, pleura, and brain.
Dan Tian +11 more
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Public health determinants of screening accessibility, diagnostic and treatment timeliness, care adherence, and survival outcomes in breast cancer patients [PDF]
Frontiers in Public HealthBackgroundDisparities in public health infrastructure, healthcare access, and system-level support contribute to delays in breast cancer screening, diagnosis, treatment initiation, and adherence to care, leading to advanced-stage presentation and poorer ...
Meixia Zhang +4 more
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Chronic Brucella infection associated with amyloid light chain cardiac amyloidosis: a case report [PDF]
Frontiers in Cardiovascular MedicineBackgroundAmyloidosis is a rare group of diseases characterized by extracellular deposition of amyloid fibrils. The most common types are amyloid light chain (AL) and transthyretin (ATTR), while serum amyloid A (AA) type is relatively rare.
RuiXia He +8 more
doaj +2 more sources
Transcriptomic and single-cell analyses reveal the prognostic value of ETV4 and its role in shaping the immune landscape of colorectal cancer [PDF]
Translational OncologyBackground: Colorectal cancer (CRC) remains a major health threat with poor prognosis in advanced stages. The transcription factor ETV4 (ETS translocation variant 4) has been implicated in various cancers, but its specific role, prognostic value, and ...
Ruipeng Meng +9 more
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Dizhi lixue xuebao, 2023 The western margin of the Ordos Basin and its adjacent regions have undergone a complex tectonic evolution from the Mesozoic to the Cenozoic era. However, the question of tectonic uplift since the Cenozoic era remains a topic of contention, and the ...
TIAN Zhaoyang +5 more
doaj +1 more source
Dizhi lixue xuebao, 2021 Divide is a dynamic feature of a landscape that routinely migrates, either through progressive or discrete river capture, in some cases even leading to the complete reorganization of river networks.
LIN Lingling +3 more
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miR-96 Inhibits SV2C to Promote Depression-Like Behavior and Memory Disorders in Mice
Frontiers in Behavioral Neuroscience, 2021 Accumulating evidence continues to emphasize the role of microRNAs as significant contributors to depression-like behavior and memory disorders. The current study aimed to investigate the mechanism by which miR-96 influences depression-like behavior and ...
Lidong Sun +6 more
doaj +1 more source
Geomatics, Natural Hazards & Risk, 2023 Analyzing and optimizing the spatio-temporal characteristics of terrestrial ecosystem carbon storage, as well as examining their coupling and coordination relationships with industrial mining land and landscape pattern, can become a reference in the ...
Junjie Dong +4 more
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Progress in Research on Antitumor Drugs and Dynamic Changes in Skeletal Muscles
Frontiers in Pharmacology, 2022 Objective: To review the research progress of reltionship between antitumor drugs and the dynamic changes of the skeletal muscles during treatment phase.Background: Sarcopenia is a common disease in patients with tumors, and it has been agreed that ...
Ting Xu +15 more
doaj +1 more source
The Influence of Travel Expectation Theory on RV Travel Consumption Decision [PDF]
E3S Web of Conferences, 2021 With the improvement of people’s quality of life, driven by consumer demand such as “self-drive tour” and “RV travel”, the RV market in China is growing rapidly.
Xuefeng Yang +5 more
doaj +1 more source