Results 221 to 230 of about 1,063,748 (327)

Causal Effects of Hydrophilic Bile Acids on Carfilzomib‐Related Cardiovascular Events in Multiple Myeloma: A Mendelian Randomization Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Carfilzomib is highly effective in the treatment of multiple myeloma, but it has been associated with cardiovascular adverse events that impact patient outcomes. Our prior global metabolomic analyses indicated an association between hydrophilic bile acids and carfilzomib‐cardiotoxicity risk, although a causal relationship remained to be determined ...
Samia Shabnaz   +15 more
wiley   +1 more source

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki   +6 more
wiley   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell   +3 more
wiley   +1 more source

Eating Disorder Risk and Diagnosis Among East Asian Youth in the United States: Findings From the Healthy Minds Study, 2020–2023

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To estimate the prevalence of probable eating disorders and self‐reported eating disorder diagnoses among East Asian young adults aged 18–25 years across US colleges. Method Using data from the 2020 to 2023 Healthy Minds Study, a repeated cross‐sectional survey of US college students, we analyzed data from East Asian and White ...
Chloe Gao   +11 more
wiley   +1 more source

The Associations Between Vegetarian and Vegan Diets and Orthorexia Nervosa Symptoms in Adults: A Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To synthesize the evidence on the associations between vegetarian and/or vegan diets (VVDs) and symptoms of orthorexia nervosa (ON) compared with omnivorous diets in the adult population. Method Following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) and the Meta‐analyses of Observational Studies in ...
Valentina Díaz‐Goñi   +9 more
wiley   +1 more source

Patterns of Uptake, Engagement, and Attrition in Randomized Controlled Trials of Digital Interventions for Eating Disorders: A Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This review aimed to quantify rates of uptake (treatment initiation), adherence (program completion), and attrition (study dropout) in randomized trials of digital eating disorder (ED) interventions, and to synthesize engagement reporting practices, their consistency, and associations with clinical outcomes. Methods Randomized trials
Claudia Liu   +4 more
wiley   +1 more source

Developing a macroecology for human‐altered ecosystems

open access: yesEcography, EarlyView.
Although anthropogenically‐induced ecological disruptions are fundamentally important in defining ecosystem properties, they are largely overlooked by macroecological theory. Anthropogenic disruptions and their effects are generally not comparable to one another, nor to disturbances that are part of natural disturbance regimes.
Erica A. Newman   +7 more
wiley   +1 more source

Synergistic Enhancement of Modified‐PVDF Humidity Sensitivity via Chemical Adsorption‐Ionic Conductivity and its Application in Intelligent Powered Air‐Purifying Respirator

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The study developed a PVDF/SiO2 humidity sensor with superhydrophobic properties and integrated the humidity sensor into the intelligent powered air‐purifying respirator (IPAPR) for breath monitoring. Coupled with the Gated Recurrent Unit (GRU) machine learning prediction algorithm, it enables feedforward control of the fan to achieve respiratory ...
Xinjian He   +9 more
wiley   +1 more source

Machine Learning–Enhanced Fluorescence Cryptography with NADH‐Responsive Polymer Dots

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study presents a smart anticounterfeiting system using semiconducting polymer dots (Pdots) that exhibit tunable fluorescence responses to NADH. By integrating these dynamic optical signals with machine learning–based decoding, the work establishes a secure and intelligent encryption platform, showing a novel strategy that links chemical sensing ...
Zhengkun Zhan   +7 more
wiley   +1 more source

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