Results 21 to 30 of about 324,566 (233)
Şâfiî Mezhebinde Örf ve Âdetin Yeri ve Kaynak Değeri
Hukukun sosyal hayata uyumunu sağlayan örf ve âdet usul kurallarının belirlenmesi ve fıkhî meselelere çözümler sunması noktasında başvurulması gereken sosyal normdur.
Mehmet Selim Aslan
doaj +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Background: Coronavirus disease 2019 (COVID-19) pandemic began in India in 2020. Despite successful vaccination, cases again started increasing from mid-December 2021.
Suvarna A Joshi +5 more
doaj +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Rezension: Armin Wolf - Wozu brauchen wir noch Journalisten?
Armin Wolf, der wohl bekannteste ORF Journalist, bringt gut lesbar Einblicke und Analysen über die Anforderungen an JournalistInnen, das Mediennutzungsverhalten von KonsumentInnen und die strategischen Überlegungen zur Reaktion auf eine zunehmende ...
Christian Berger
doaj +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Fernsehen zum Fernhalten von Faschismus
Gestaltet als essayistische Zeitdiagnose und medienkritische Materialanalyse, widmet sich dieser Text Sendungen des öffentlich-rechtliche Fernsehen ORF von 2018, zum 80.
Drehli Robnik, Renée Winter
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MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source

