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Genomic Differences and Mutations in Epidemic Orf Virus and Vaccine Strains: Implications for Improving Orf Virus Vaccines [PDF]

open access: yesVeterinary Sciences
Orf (ORF) is an acute disease caused by the Orf virus (ORFV), and poses a certain threat to animal and human health. Live attenuated vaccines play an important role in the prevention and control of ORF.
Dengshuai Zhao   +7 more
doaj   +4 more sources

A rare case of human infection with Orf virus in China, 2024 [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology
Orf virus is a globally distributed zoonotic pathogen that mainly infects sheep and goats, although cases of human infection have been occasionally reported. In this study, we reported a rare case of human infection with Orf virus in China. A 66-year-old
Miao Lu   +8 more
doaj   +2 more sources

Orf Virus Detection in the Saliva and Milk of Dairy Goats [PDF]

open access: yesFrontiers in Microbiology, 2022
Orf is a zoonotic and highly contagious disease caused by Orf virus (ORFV) infection. Orf outbreaks in sheep and goats usually lead to high culling rate and mortality in newborn kids and lambs, posing a great threat to the development of goat and sheep ...
Wentao Ma   +6 more
doaj   +2 more sources

The Role of Neutrophils in Oncolytic Orf Virus-Mediated Cancer Immunotherapy [PDF]

open access: yesCells, 2022
Neutrophils are innate leukocytes with diverse effector functions that allow them to respond to pathogens rapidly. Accumulating evidence has highlighted these cells’ complex roles in the host’s response to viral infections and tumor progression ...
Jessica A. Minott   +5 more
doaj   +2 more sources

A novel ORF127/ORF130 gene deletion Orf virus vaccine candidate: construction and evaluation [PDF]

open access: yesVirology Journal
Background Orf is a zoonotic infectious disease caused by the Orf virus (ORFV), posing a serious threat to the health of ruminants and humans. Vaccination remains the most effective strategy for disease control.
Guangxiang Wang   +5 more
doaj   +2 more sources

An evaluation of the ecological niche of Orf virus (Poxviridae): Challenges of distinguishing broad niches from no niches. [PDF]

open access: yesPLoS ONE
Contagious ecthyma is a skin disease, caused by Orf virus, creating great economic threats to livestock farming worldwide. Zoonotic potential of this disease has gained recent attention owing to the re-emergence of disease in several parts of the world ...
Rahul Raveendran Nair   +2 more
doaj   +2 more sources

A Rare Case of Orf Virus Precipitating Methicillin-Resistant Staphylococcus Aureus Bacteremia Superinfection Leading to Native Hip Joint Septic Arthritis [PDF]

open access: yesJournal of Orthopaedic Case Reports
Introduction: Orf disease, or Ecthyma contagiosum, is a zoonotic skin infection caused by the orf virus. The orf virus belongs to the family parapoxvirus and is commonly seen in sheep, goats, and deer.
Alexander Price   +4 more
doaj   +2 more sources

[Translated article] Orf Virus Nodule

open access: yesActas Dermo-Sifiliográficas
P. López Sanz   +2 more
doaj   +3 more sources

APPLICATION OF REAL TIME PCR FOR IDENTIFICATION OF SHEEP POXVIRUS, CAMEL POXVIRUS AND CONTAGIOUS ECTHYMA VIRUS ISOLATES [PDF]

open access: yesVeterinary Medical Journal - Giza, 2008
Recently, attention has been directed toward the application of Real time -PCR assays as a rapid and accurate tools for identification of Capripox, Parapox and Orthopox viruses that cause devastating diseases in farm animals in the Kingdom of Saudi ...
Abdel Baky, M H   +9 more
doaj   +1 more source

Heterogeneity among orf virus isolates from goats in Fujian Province, Southern China. [PDF]

open access: yesPLoS ONE, 2013
Orf virus is a parapoxvirus that causes recurring contagious ecthyma or orf disease in goat, sheep and other wild and domestic ruminants. Infected animals show signs of pustular lesions on the mouth and muzzle and develop scabs over the lesions. Although
Xuelin Chi   +7 more
doaj   +1 more source

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