Genomic Differences and Mutations in Epidemic Orf Virus and Vaccine Strains: Implications for Improving Orf Virus Vaccines [PDF]
Veterinary SciencesOrf (ORF) is an acute disease caused by the Orf virus (ORFV), and poses a certain threat to animal and human health. Live attenuated vaccines play an important role in the prevention and control of ORF.
Dengshuai Zhao +7 more
doaj +4 more sources
A rare case of human infection with Orf virus in China, 2024 [PDF]
Frontiers in Cellular and Infection MicrobiologyOrf virus is a globally distributed zoonotic pathogen that mainly infects sheep and goats, although cases of human infection have been occasionally reported. In this study, we reported a rare case of human infection with Orf virus in China. A 66-year-old
Miao Lu +8 more
doaj +2 more sources
Orf Virus Detection in the Saliva and Milk of Dairy Goats [PDF]
Frontiers in Microbiology, 2022 Orf is a zoonotic and highly contagious disease caused by Orf virus (ORFV) infection. Orf outbreaks in sheep and goats usually lead to high culling rate and mortality in newborn kids and lambs, posing a great threat to the development of goat and sheep ...
Wentao Ma +6 more
doaj +2 more sources
Orf virus infection after Eid al-Adha
IDCases, 2020 Human orf, also called ecthyma contagiosum, is a zoonotic infection that causes self-resolving skin lesions after contact with infected livestock.
Ashley Vellucci +7 more
doaj +3 more sources
Reverse genetic characterization of the natural genomic deletion in SARS-Coronavirus strain Frankfurt-1 open reading frame 7b reveals an attenuating function of the 7b protein
Virology Journal, 2009 During the outbreak of SARS in 2002/3, a prototype virus was isolated from a patient in Frankfurt/Germany (strain Frankfurt-1). As opposed to all other SARS-Coronavirus strains, Frankfurt-1 has a 45-nucleotide deletion in the transmembrane domain of its ...
Grywna Klaus +5 more
doaj +5 more sources
The Role of Neutrophils in Oncolytic Orf Virus-Mediated Cancer Immunotherapy [PDF]
Cells, 2022 Neutrophils are innate leukocytes with diverse effector functions that allow them to respond to pathogens rapidly. Accumulating evidence has highlighted these cells’ complex roles in the host’s response to viral infections and tumor progression ...
Jessica A. Minott +5 more
doaj +2 more sources
A novel ORF127/ORF130 gene deletion Orf virus vaccine candidate: construction and evaluation [PDF]
Virology JournalBackground Orf is a zoonotic infectious disease caused by the Orf virus (ORFV), posing a serious threat to the health of ruminants and humans. Vaccination remains the most effective strategy for disease control.
Guangxiang Wang +5 more
doaj +2 more sources
An evaluation of the ecological niche of Orf virus (Poxviridae): Challenges of distinguishing broad niches from no niches. [PDF]
PLoS ONEContagious ecthyma is a skin disease, caused by Orf virus, creating great economic threats to livestock farming worldwide. Zoonotic potential of this disease has gained recent attention owing to the re-emergence of disease in several parts of the world ...
Rahul Raveendran Nair +2 more
doaj +2 more sources
A Rare Case of Orf Virus Precipitating Methicillin-Resistant Staphylococcus Aureus Bacteremia Superinfection Leading to Native Hip Joint Septic Arthritis [PDF]
Journal of Orthopaedic Case ReportsIntroduction: Orf disease, or Ecthyma contagiosum, is a zoonotic skin infection caused by the orf virus. The orf virus belongs to the family parapoxvirus and is commonly seen in sheep, goats, and deer.
Alexander Price +4 more
doaj +2 more sources
[Translated article] Orf Virus Nodule
Actas Dermo-SifiliográficasP. López Sanz +2 more
doaj +2 more sources