Results 1 to 10 of about 150,284 (337)
Peptides Encoded by Short ORFs Control Development and Define a New Eukaryotic Gene Family
PLoS Biology, 2007 Despite recent advances in developmental biology, and the sequencing and annotation of genomes, key questions regarding the organisation of cells into embryos remain.
Máximo Ibo Galindo +2 more
exaly +3 more sources
eIF4G is retained on ribosomes elongating and terminating on short upstream ORFs to control reinitiation in yeast [PDF]
Nucleic Acids Research, 2021 Mahabub Pasha Mohammad, Leoš Valášek
exaly +2 more sources
RiboNT: A Noise-Tolerant Predictor of Open Reading Frames from Ribosome-Protected Footprints
Life, 2021 Ribo-seq, also known as ribosome profiling, refers to the sequencing of ribosome-protected mRNA fragments (RPFs). This technique has greatly advanced our understanding of translation and facilitated the identification of novel open reading frames (ORFs ...
Bo Song, Mengyun Jiang, Lei Gao
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Pervasive translation in Mycobacterium tuberculosis
eLife, 2022 Most bacterial ORFs are identified by automated prediction algorithms. However, these algorithms often fail to identify ORFs lacking canonical features such as a length of >50 codons or the presence of an upstream Shine-Dalgarno sequence. Here, we use
Carol Smith +6 more
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Landscape of the Dark Transcriptome Revealed Through Re-mining Massive RNA-Seq Data
Frontiers in Genetics, 2021 The “dark transcriptome” can be considered the multitude of sequences that are transcribed but not annotated as genes. We evaluated expression of 6,692 annotated genes and 29,354 unannotated open reading frames (ORFs) in the Saccharomyces cerevisiae ...
Jing Li +12 more
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Mobile DNA, 2020 Background Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections of mammalian germline cells. A large proportion of ERVs lose their open reading frames (ORFs), while others retain them and become exapted by the host species ...
Mahoko Takahashi Ueda +5 more
doaj +1 more source
BMC Genomics, 2022 Background Arcidae, comprising about 260 species of ark shells, is an ecologically and economically important lineage of bivalve mollusks. Interestingly, mitochondrial genomes of several Arcidae species are 2–3 times larger than those of most bilaterians,
Ning Zhang +4 more
doaj +1 more source
Re-annotation of protein-coding genes in the genome of saccharomyces cerevisiae based on support vector machines. [PDF]
PLoS ONE, 2013 The annotation of the well-studied organism, Saccharomyces cerevisiae, has been improving over the past decade while there are unresolved debates over the amount of biologically significant open reading frames (ORFs) in yeast genome.
Dan Lin +4 more
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Synthesis and assembly of full-length cyanophage A-4L genome
Synthetic and Systems Biotechnology, 2023 Artificial cyanophages are considered to be an effective biological method to control harmful cyanobacterial bloom. However, no synthetic cyanophage genome has been constructed and where its obstacles are unclear.
Ting Zhang +7 more
doaj +1 more source
PLoS ONE, 2021 In this study, the genomes of three Plutella xylostella granulovirus (PlxyGV) isolates, PlxyGV-W and PlxyGV-Wn from near Wuhan and PlxyGV-B from near Beijing, China were completely sequenced and comparatively analyzed to investigate genetic stability and
Man-Li Zhang +5 more
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