Results 181 to 190 of about 104,420 (304)

A distinct gene expression mechanism for d‐amino acid utilization in hyperthermophilic archaeon Pyrococcus horikoshii

The FEBS Journal, EarlyView.
The genes PH0137, PH0138, and PH0140 form a cluster in the genome of Pyrococcus horikoshii. The PH0140 gene encodes a transcription factor identified as a d‐amino acid‐responsive regulatory protein (DARP). In feast mode, l‐Ile‐bound DARP binds to the promoter and represses transcription of PH0137 and PH0138. In famine mode, DARP binds to d‐allo‐Ile and
Ryushi Kawakami, Tomoki Kawase, Taira Uehara, Haruhiko Sakuraba, Tomohiko Matsuzawa, Junji Hayashi, Toshihisa Ohshima   +6 more
wiley   +1 more source

NeuroViOme: a viral orfeome collection for studies of neurodegenerative disease. [PDF]

J Neurovirol
Weller B, Lin CW, Rothballer S, Calderwood MA, Falter-Braun P, Falter C.   +5 more
europepmc   +1 more source

Inducing Antigen‐Specific and Functional Immune Responses in Mice Toward Bovine Herpesvirus 1 and Bovine Respiratory Syncytial Virus by Chimeric Peptides Delivered by Bovine Herpesvirus 4‐Based Vector

Immunology, EarlyView.
Bovine Alphaherpesvirus 1 (BoHV‐1) and Bovine respiratory syncytial virus (BRSV) are major drivers of respiratory disease in cattle. (A) To target both pathogens, two chimeric antigens—membrane‐linked and secreted—combining BoHV‐1 glycoprotein D and BRSV fusion glycoprotein were designed and expressed using recombinant BoHV‐4‐based vectors.
Antonino Di Lorenzo, Sergio Minesso, Chiara Cossu, Valentina Franceschi, Elisabetta Bolli, Vittorio Madia, Laura Conti, Gaetano Donofrio   +7 more
wiley   +1 more source

Characterisation of HIV‐1 Gag Cytotoxic T‐Lymphocyte Epitopes in the Southern African Region—A Systematic Review

Immunology, EarlyView.
Distribution of studies on HIV‐1 Gag cytotoxic T‐lymphocyte epitopes in the southern African region showing that the majority of studies (58.44%) were conducted in South Africa, followed by Botswana (15.58%), Zambia (10.39%), Malawi (7.79%), Zimbabwe (6.49%), and Angola (1.30%).
Tumelo L. Fortuin, Paballo Nkone, Shayne Loubser, Caroline T. Tiemessen, Simnikiwe H. Mayaphi   +4 more
wiley   +1 more source

Identification and characterization of an endogenous pararetrovirus in Gentiana triflora plants. [PDF]

Arch Virol
Isogai M, Tezuka S, Abe A, Takamura Y, Yaegashi H.   +4 more
europepmc   +1 more source

Senescent Human Liver Endothelial Cells Mediate CD4+ T Cell Recruitment via ICOSL

Immunology, EarlyView.
In this study, we detect senescent endothelial cells within chronically diseased human liver tissues. Next, we develop a novel protocol for the induction of paracrine senescence in primary human liver endothelial cells and explore their functionality.
Daniel A. Patten, Amy Lumley, Alex L. Wilkinson, Ayla O’Keeffe, Kelvin Yin, Niranjan Shirgaonkar, Ran Gao, Ramanuj DasGupta, Matthew Hoare, Shishir Shetty   +9 more
wiley   +1 more source

Size‐, sex‐ and site‐dependent morphological variation in the stone flounder (Kareius bicoloratus) from Korean coastal waters

Journal of Fish Biology, EarlyView.
Abstract Kareius bicoloratus is a commercially important flatfish in Korean coastal fisheries and an ecologically relevant benthic species in nearshore ecosystems. To evaluate how multiple biological and environmental factors jointly shape flatfish morphology, we analysed 81 morphometric indices and two‐dimensional geometric morphometrics (GMM) in wild
Eun Jeong Kim, Songhyun Gwon, Ju Hwan Park, In Chul Bang, Yoon Kwon Nam   +4 more
wiley   +1 more source

DeepTYLCV: An interpretable and experimentally validated AI model for predicting virulence of different tomato yellow leaf curl virus strains. [PDF]

Plant Commun
Bupi N, Sangaraju H, Tran DT, Sangaraju VK, Im H, Kim M, Lee S, Manavalan B.   +7 more
europepmc   +1 more source

Outbreaks of Granulomatous Disease Associated With Vibrio harveyi Infection in Grouper (Epinephelus fuscoguttatus × E. lanceolatus) Aquaculture in Taiwan

Journal of Fish Diseases, EarlyView.
ABSTRACT Between 2015 and 2024, outbreaks of muscular and visceral granulomatous disease, resulting in moderate‐to‐severe mortality in farmed groupers, occurred in southern Taiwan. Initially, affected groupers were screened for granuloma‐associated pathogens, including Mycobacterium spp., Nocardia spp., Photobacterium damselae and Edwardsiella spp ...
Shang‐Ting Wu, Chia‐Yu Hsieh
wiley   +1 more source

Computational optimization of two-photon holographic stimulation sites<i>in vivo</i>. [PDF]

J Neural Eng
Triplett MA, Bäumler E, Prodan A, Stonis R, Peterka DS, Häusser M, Paninski L.   +6 more
europepmc   +1 more source