Results 281 to 290 of about 61,131 (327)

Organ-on-a-Chip: Ubi sumus? Fundamentals and Design Aspects. [PDF]

open access: yesPharmaceutics
Morais AS   +6 more
europepmc   +1 more source

Functionalization of Polyethylene Terephthalate (PETE) Membranes for the Enhancement of Cellular Adhesion in Organ-on-a-Chip Devices. [PDF]

open access: yesACS Appl Mater Interfaces
Sobejano de la Merced C   +7 more
europepmc   +1 more source

Organ-on-a-Chip

2020
Limitations of the current tools used in the drug development process, cell cultures, and animal models have highlighted the need for a new powerful tool that can emulate the human physiology in vitro. Advances in the field of microfluidics have made the realization of this tool closer than ever.
Ilka, Maschmeyer, Sofia, Kakava
openaire   +3 more sources

Vat photopolymerization 3D printed microfluidic devices for organ-on-a-chip applications.

Lab on a Chip, 2023
Organs-on-a-chip, or OoCs, are microfluidic tissue culture devices with micro-scaled architectures that repeatedly achieve biomimicry of biological phenomena.
Laura A. Milton   +4 more
semanticscholar   +1 more source

Organ-on-a-Chip Platform with an Integrated Screen-Printed Electrode Array for Real-Time Monitoring Trans-Epithelial Barrier and Bubble Formation.

ACS Biomaterials Science & Engineering, 2023
Cellular tight junctions play a key role in establishing a barrier between different compartments of the body by regulating the selective passage of different solutes across epithelial and endothelial tissues.
A. Krishnakumar   +5 more
semanticscholar   +1 more source

Organs-on-a-Chip

2020
Organs-on-chips, also known as "tissue chips" or microphysiological systems (MPS), are bioengineered microsystems capable of recreating aspects of human organ physiology and function and are in vitro tools with multiple applications in drug discovery and development. The ability to recapitulate human and animal tissues in physiologically relevant three-
Lucie A, Low   +5 more
openaire   +2 more sources

Intervertebral disc organ-on-a-chip: an innovative model to study monocyte extravasation during nucleus pulposus degeneration.

Lab on a Chip, 2023
Degenerative cascades of the intervertebral disc (IVD) are characterized by the presence of immune cells like monocytes, macrophages, and leukocytes, which contribute to inflammation.
Hyeong-Guk Son   +7 more
semanticscholar   +1 more source

Organs-on-a-Chip

Scientific American, 2011
The article discusses the development of a microchip that simulates the activities and mechanics of entire organs and organ systems, called "organs on a chip." According to the author, organs on a chip would help scientists deal with some of the more challenging aspects of research, such as the need to experiment on whole animals.
openaire   +2 more sources

Engineered Biomimetic Membranes for Organ-on-a-Chip

ACS Biomaterials Science & Engineering, 2022
Organ-on-a-chip (OOC) systems are engineered nanobiosystems to mimic the physiochemical environment of a specific organ in the body. Among various components of OOC systems, biomimetic membranes have been regarded as one of the most important key components to develop controllable biomimetic bioanalysis systems.
Maedeh Rahimnejad   +12 more
openaire   +2 more sources

Organ-on-a-chip: key industry insights, challenges, and opportunities from 100+ NSF I-Corps interviews.

Lab on a Chip
Organ-on-a-chip (OoC) is a rapidly advancing technology with significant potential to revolutionize healthcare, drug discovery, and personalized medicine.
Ronin-Mae Komarnisky   +3 more
semanticscholar   +1 more source

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