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Organ-on-a-Chip: Ubi sumus? Fundamentals and Design Aspects. [PDF]
Morais AS +6 more
europepmc +1 more source
Functionalization of Polyethylene Terephthalate (PETE) Membranes for the Enhancement of Cellular Adhesion in Organ-on-a-Chip Devices. [PDF]
Sobejano de la Merced C +7 more
europepmc +1 more source
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2020
Limitations of the current tools used in the drug development process, cell cultures, and animal models have highlighted the need for a new powerful tool that can emulate the human physiology in vitro. Advances in the field of microfluidics have made the realization of this tool closer than ever.
Ilka, Maschmeyer, Sofia, Kakava
openaire +3 more sources
Limitations of the current tools used in the drug development process, cell cultures, and animal models have highlighted the need for a new powerful tool that can emulate the human physiology in vitro. Advances in the field of microfluidics have made the realization of this tool closer than ever.
Ilka, Maschmeyer, Sofia, Kakava
openaire +3 more sources
Vat photopolymerization 3D printed microfluidic devices for organ-on-a-chip applications.
Lab on a Chip, 2023Organs-on-a-chip, or OoCs, are microfluidic tissue culture devices with micro-scaled architectures that repeatedly achieve biomimicry of biological phenomena.
Laura A. Milton +4 more
semanticscholar +1 more source
ACS Biomaterials Science & Engineering, 2023
Cellular tight junctions play a key role in establishing a barrier between different compartments of the body by regulating the selective passage of different solutes across epithelial and endothelial tissues.
A. Krishnakumar +5 more
semanticscholar +1 more source
Cellular tight junctions play a key role in establishing a barrier between different compartments of the body by regulating the selective passage of different solutes across epithelial and endothelial tissues.
A. Krishnakumar +5 more
semanticscholar +1 more source
2020
Organs-on-chips, also known as "tissue chips" or microphysiological systems (MPS), are bioengineered microsystems capable of recreating aspects of human organ physiology and function and are in vitro tools with multiple applications in drug discovery and development. The ability to recapitulate human and animal tissues in physiologically relevant three-
Lucie A, Low +5 more
openaire +2 more sources
Organs-on-chips, also known as "tissue chips" or microphysiological systems (MPS), are bioengineered microsystems capable of recreating aspects of human organ physiology and function and are in vitro tools with multiple applications in drug discovery and development. The ability to recapitulate human and animal tissues in physiologically relevant three-
Lucie A, Low +5 more
openaire +2 more sources
Lab on a Chip, 2023
Degenerative cascades of the intervertebral disc (IVD) are characterized by the presence of immune cells like monocytes, macrophages, and leukocytes, which contribute to inflammation.
Hyeong-Guk Son +7 more
semanticscholar +1 more source
Degenerative cascades of the intervertebral disc (IVD) are characterized by the presence of immune cells like monocytes, macrophages, and leukocytes, which contribute to inflammation.
Hyeong-Guk Son +7 more
semanticscholar +1 more source
Scientific American, 2011
The article discusses the development of a microchip that simulates the activities and mechanics of entire organs and organ systems, called "organs on a chip." According to the author, organs on a chip would help scientists deal with some of the more challenging aspects of research, such as the need to experiment on whole animals.
openaire +2 more sources
The article discusses the development of a microchip that simulates the activities and mechanics of entire organs and organ systems, called "organs on a chip." According to the author, organs on a chip would help scientists deal with some of the more challenging aspects of research, such as the need to experiment on whole animals.
openaire +2 more sources
Engineered Biomimetic Membranes for Organ-on-a-Chip
ACS Biomaterials Science & Engineering, 2022Organ-on-a-chip (OOC) systems are engineered nanobiosystems to mimic the physiochemical environment of a specific organ in the body. Among various components of OOC systems, biomimetic membranes have been regarded as one of the most important key components to develop controllable biomimetic bioanalysis systems.
Maedeh Rahimnejad +12 more
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Lab on a Chip
Organ-on-a-chip (OoC) is a rapidly advancing technology with significant potential to revolutionize healthcare, drug discovery, and personalized medicine.
Ronin-Mae Komarnisky +3 more
semanticscholar +1 more source
Organ-on-a-chip (OoC) is a rapidly advancing technology with significant potential to revolutionize healthcare, drug discovery, and personalized medicine.
Ronin-Mae Komarnisky +3 more
semanticscholar +1 more source

