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Organs-on-a-chip models for biological research

Cell, 2021
We explore the utility of bioengineered human tissues-individually or connected into physiological units-for biological research. While much smaller and simpler than their native counterparts, these tissues are complex enough to approximate distinct tissue phenotypes: molecular, structural, and functional. Unlike organoids, which form spontaneously and
Gordana, Vunjak-Novakovic   +2 more
openaire   +2 more sources

Sensors and Biosensors in Organs-on-a-Chip Platforms

2022
Biosensors represent a powerful analytical tool for analyzing biomolecular interactions with the potential to achieve real-time quantitative analysis with high accuracy using low sample volumes, minimum sample pretreatment with high potential for the development of in situ and highly integrated monitoring platforms.
Gerardo A, Lopez-Muñoz   +2 more
openaire   +2 more sources

Organ-on-a-Chip

The Meducator, 2023
Anna McCracken, Raymond Qu
openaire   +2 more sources

Advances in Hydrogels in Organoids and Organs‐on‐a‐Chip

Advanced Materials, 2019
AbstractSignificant advances in materials, microscale technology, and stem cell biology have enabled the construction of 3D tissues and organs, which will ultimately lead to more effective diagnostics and therapy. Organoids and organs‐on‐a‐chip (OOC), evolved from developmental biology and bioengineering principles, have emerged as major technological ...
Haitao Liu   +5 more
openaire   +2 more sources

Organ-on-a-chip Systems

2017
Organ-on-a-chip systems are novel platforms, which imitate key functions of living organ, including specific microarchitectures, cell–cell and tissue–tissue interactions, and extracellular communication. Microtechnology offers the possibility of creating more complex, multi-organ platforms known as Body-on-a-chip or Human-on-a-chip.
Aleksandra Szuplewska   +2 more
openaire   +1 more source

Microfluidic bioprinting for organ-on-a-chip models

Drug Discovery Today, 2019
Bioprinting is a revolutionary technology to assemble scaffolds for growing tissues. Microfluidic organs-on-a-chip is a useful platform with widespread applications mainly in drug screening and pathological studies. Organ-on-a-chip models are created to recapitulate the structural, microenvironmental and physiological functions of human organs ...
Fang, Yu, Deepak, Choudhury
openaire   +2 more sources

Organ-on-a-Chip: A New Paradigm for Drug Development

Trends in Pharmacological Sciences, 2021
Chao Ma, Yansong Peng, Weiqiang Chen
exaly  

Organ-on-a-chip: A new tool for research

Biosensors and Bioelectronics, 2022
Jinhong Guo, Jiuchuan Guo
exaly  

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