Results 251 to 260 of about 127,842,725 (298)

Modeling of lung-liver interaction during infection in a human fluidic organ-on-a-chip. [PDF]

open access: yesSci Rep
Reinhold S   +11 more
europepmc   +1 more source

Organ-on-a-chip systems for vascular biology

Journal of Molecular and Cellular Cardiology, 2021
Organ-on-a-chip (OOC) platforms involve the miniaturization of cell culture systems and enable a variety of novel experimental approaches. These range from modeling the independent effects of biophysical forces on cells to screening novel drugs in multi-organ microphysiological systems, all within microscale devices.
Samuel G Rayner   +2 more
exaly   +3 more sources

Organs-on-a-Chip

2020
Organs-on-chips, also known as "tissue chips" or microphysiological systems (MPS), are bioengineered microsystems capable of recreating aspects of human organ physiology and function and are in vitro tools with multiple applications in drug discovery and development. The ability to recapitulate human and animal tissues in physiologically relevant three-
Lucie A, Low   +5 more
openaire   +2 more sources

Organs-on-a-Chip

Scientific American, 2011
The article discusses the development of a microchip that simulates the activities and mechanics of entire organs and organ systems, called "organs on a chip." According to the author, organs on a chip would help scientists deal with some of the more challenging aspects of research, such as the need to experiment on whole animals.
openaire   +2 more sources

Organs-on-a-Chip

2021
Abstract Abstract: This chapter explores organs-on-a-chip, miniaturized bioprinted organ tissues enclosed in a microfluidic housing (microfluidics refers to very small-scale plumbing) that can mimic functions of human physiology or disease and are particularly effective when multiple tissue types—for example, lung, heart, and liver—can ...
openaire   +1 more source

Organs-on-a-chip for drug discovery

Current Opinion in Pharmacology, 2013
The current drug discovery process is arduous and costly, and a majority of the drug candidates entering clinical trials fail to make it to the marketplace. The standard static well culture approaches, although useful, do not fully capture the intricate in vivo environment.
Seila, Selimović   +2 more
openaire   +2 more sources

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