Results 251 to 260 of about 91,588,802 (303)

Potential of organ-on-a-chip in advancing synthetic extracellular matrix technology for bone tissue engineering in dentistry (Review). [PDF]

Biomed Rep
Syahruddin MH, Ana ID, Belyaev D, Irnawati D, Wihadmadyatami H, Beshchasna N, Anggraeni R.   +6 more
europepmc   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Innovative organ-on-a-chip platforms for exploring tumorigenesis and therapy in head and neck cancer. [PDF]

J Transl Med
Lin C, Zhang Z, Yang F, Gu S, Zuo J, Wu Y, Zhang J, Zhou T, Zhang Y, Chen Z, Gu Z, Shen Z.   +11 more
europepmc   +1 more source

An Organ-on-a-Chip Modular Platform with Integrated Immunobiosensors for Monitoring the Extracellular Environment. [PDF]

Micromachines (Basel)
Kanioura A, Filippidou MK, Tsounidi D, Petrou PS, Chatzandroulis S, Tserepi A.   +5 more
europepmc   +1 more source

Organoid, organ-on-a-chip and traditional Chinese medicine. [PDF]

Chin Med
Yang J, Jiang Y, Li M, Wu K, Wei S, Zhao Y, Shen J, Du F, Chen Y, Deng S, Xiao Z, Yuan W, Wu X.   +12 more
europepmc   +1 more source

Porcine intestinal organoids cultured in an organ-on-a-chip microphysiological system. [PDF]

Biochem Biophys Rep
Bacon J, Kitchel H, Stutz J, Chen JH, Smith A, Van Horn RD, Moreland C, Abraham T, Baker T, Aihara E, Hillgren K.   +10 more
europepmc   +1 more source

Physical model of serum supplemented medium flow in organ-on-a-chip systems. [PDF]

PLoS One
Šints V, Cīmurs J, Birjukovs M, Driķis I, Goluba K, Jēkabsons K, Parfejevs V, Riekstiņa U, Mozoļevskis G, Rimša R, Kitenbergs G.   +10 more
europepmc   +1 more source

Mechanisms and safety evaluation of stir-fried atractylodis macrocephalae rhizoma with aurantii fructus in the treatment of inflammatory bowel disease: a study based on organ-on-a-chip model. [PDF]

Front Pharmacol
Zhang W, Liu C, Chen W, Zhu Y, Gu Z, Xue P, Zhuang X, Wei Y, Ye J, Xu X, Zhang J, Chen Z, Gu Z, Hua F.   +13 more
europepmc   +1 more source

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Organ-on-a-chip systems for vascular biology

Journal of Molecular and Cellular Cardiology, 2021
Organ-on-a-chip (OOC) platforms involve the miniaturization of cell culture systems and enable a variety of novel experimental approaches. These range from modeling the independent effects of biophysical forces on cells to screening novel drugs in multi-organ microphysiological systems, all within microscale devices.
Christian Mandrycky, Samuel G Rayner, Ying Zheng   +2 more
exaly   +3 more sources