Results 141 to 150 of about 69,325 (340)

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Soft tubular microfluidics for 2D and 3D applications [PDF]

, 2017
Microfluidics has been the key component for many applications, including biomedical devices, chemical processors, microactuators, and even wearable devices.
Dao, Ming, Gong, Xiaobo, Kong, Fang, Lim, Chwee Teck, Sonam, Surabhi, Xi, Wang, Yeo, Joo Chuan, Yu, Longteng   +7 more
core   +1 more source

Triplet‐Triplet Annihilation Enhances Photochemical Curing Contrast for Vat‐Based 3D Printing

Advanced Functional Materials, EarlyView.
Triplet–triplet annihilation photopolymerization (TTAP) resins enhance curing contrast for digital light processing (DLP) 3D printing compared to conventional Type I and II photopolymerizations at matched optical densities. By exploiting a superlinear initiation response, TTAP preserves fine details, allowing reliable fabrication of complex structures ...
Connor J. O'Dea, Evan P. Scruggs, Zachariah A. Page   +2 more
wiley   +1 more source

Anti-Inflammatory and Regenerative Properties of Herbal Extracts: Wound Management in Equine Models

Drug Target Insights
Introduction: Wound management presents significant challenges, requiring effective treatments. Herbal extracts have been traditionally used to support healing due to their anti-inflammatory, antimicrobial, and cellregenerative properties. Methods: This
Gustavo Fehrenbach, Katie Shiels, Mariana Juca Silva, Jessica Walshe, Lena Madden, Ian Major, Niall Burke, Tim Yeomans, Emanuele Rezoagli, Emma Murphy   +9 more
doaj   +1 more source

Parallel 3D Bioprinting on SLIPS‐Microarrays

Advanced Functional Materials, EarlyView.
This work introduces the first truly parallel 3D bioprinting method, enabling both the simultaneous fabrication of hundreds of cell laden hydrogel 3D structures and their HTS in individual liquid compartments. By integrating Digital Light Processing (DLP) stereolithography with functional micropatterns, the platform decouples printing time from array ...
Julius von Padberg, Julian A. Serna, Maike Schliephake, Pavel A. Levkin   +3 more
wiley   +1 more source

Melanoma-on-a-chip model for anticancer drug injecting delivery method

SLAS Technology
The pharmaceutical and cosmetic industries are encountering a challenge in adopting new study models for product development. there has been a growing interest in organ-on-a-chip systems, and particularly for generating skin models.
Pedro Herreros, Ana López-Hernández, Miguel Holgado, María Fe Laguna Heras   +3 more
doaj   +1 more source

Hemostasis-On-a-Chip: Impedance Spectroscopy Meets Microfluidics for Hemostasis Evaluation

Micromachines, 2019
In the case of vascular injury, a complex process (of clotting) starts, involving mainly platelets and coagulation factors. This process in healthy humans is known as hemostasis, but when it is deregulated (thrombosis), it can be the cause of important ...
Shadi Karimi, Josep Farré-Lladós, Enrique Mir, Ginés Escolar, Jasmina Casals-Terré   +4 more
doaj   +1 more source

State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology. [PDF]

, 2014
Integrated approaches using different in vitro methods in combination with bioinformatics can (i) increase the success rate and speed of drug development; (ii) improve the accuracy of toxicological risk assessment; and (iii) increase our understanding of
Alépée, N., Bahinski, A., Daneshian, M., De Wever, B., Fritsche, E., Goldberg, A., Hansmann, J., Hartung, T., Haycock, J., Hoelting, L., Hogberg, H., Kadereit, S., Kelm, J.M., Landsiedel, R., Leist, M., Lübberstedt, M., McVey, E., Noor, F., Pellevoisin, C., Petersohn, D., Pfannenbecker, U., Ramirez, T., Reisinger, K., Rothen-Rutishauser, B., Schäfer-Korting, M., Zeilinger, K., Zurich, M.G.   +26 more
core   +3 more sources

Toxicokinetics for organ-on-chip devices

Lab on a Chip
Abstract Organ-on-chip (OOC) devices are an emerging New Approach Method in both pharmacology and toxicology. Such devices use heterotypic combinations of human cells in a micro-fabricated device to mimic in vivo conditions and better predict organ-specific toxicological responses ...
Nathaniel G. Hermann, Richard A. Ficek, Dmitry A. Markov, Lisa J. McCawley, M. Shane Hutson   +4 more
openaire   +2 more sources

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source