Results 1 to 10 of about 790,004 (346)

Design and Fabrication of Organ-on-Chips: Promises and Challenges

Micromachines, 2021
The advent of the miniaturization approach has influenced the research trends in almost all disciplines. Bioengineering is one of the fields benefiting from the new possibilities of microfabrication techniques, especially in cell and tissue culture ...
Alireza Tajeddin, Nur Mustafaoglu
doaj   +2 more sources

Biological Effects of Clinically Relevant CoCr Nanoparticles in the Dura Mater: An Organ Culture Study [PDF]

Nanomaterials, 2014
Medical interventions for the treatment of spinal disc degeneration include total disc replacement and fusion devices. There are, however, concerns regarding the generation of wear particles by these devices, the majority of which are in the nanometre ...
Iraklis Papageorgiou, Thomas Abberton, Martin Fuller, Joanne L. Tipper, John Fisher, Eileen Ingham   +5 more
doaj   +4 more sources

Development of an Ex Vivo Organ Culture Technique to Evaluate Probiotic Utilization in IBD [PDF]

, 2016
The consistent technical and conceptual progress in the study of the microbiota has led novel impulse to the research for therapeutical application of probiotic bacteria in human pathologies, such as inflammatory bowel disease (IBD).
Cristiano Pagnini, Michela Martorelli, Claudio Lanini, Gianfranco Delle Fave   +3 more
openalex   +4 more sources

Ex vivo development of the entire mouse fetal reproductive tract by using microdissection and membrane-based organ culture techniques. [PDF]

Differentiation, 2022
Jia S, Zhao F.
europepmc   +3 more sources

Modular automated microfluidic cell culture platform reduces glycolytic stress in cerebral cortex organoids

Scientific Reports, 2022
Organ-on-a-chip systems combine microfluidics, cell biology, and tissue engineering to culture 3D organ-specific in vitro models that recapitulate the biology and physiology of their in vivo counterparts. Here, we have developed a multiplex platform that
Spencer T. Seiler, Gary L. Mantalas, John Selberg, Sergio Cordero, Sebastian Torres-Montoya, Pierre V. Baudin, Victoria T. Ly, Finn Amend, Liam Tran, Ryan N. Hoffman, Marco Rolandi, Richard E. Green, David Haussler, Sofie R. Salama, Mircea Teodorescu   +14 more
doaj   +2 more sources

The nerve center of organ engineering [PDF]

Nature Communications
Engineering replacement organs is the next frontier in therapeutic technologies. Yet, the integration of innervation—critical for organ development, function, and homeostasis—remains underexplored.
Suradip Das, Wisberty J. Gordián-Vélez, Jay R. Dave, Zarina S. Ali, Harry C. Ledebur, D. Kacy Cullen   +5 more
doaj   +2 more sources

Application of efficient and specific gene transfer systems and organ culture techniques for the elucidation of mechanisms of epithelial– mesenchymal interaction in the developing gut [PDF]

Development, Growth and Differentiation, 2000
Kimiko Fukuda, Nobuyuki Sakamoto, Tomohiro Narita, K. Saitoh, Takashi Kameda, Hideo Iba, Sadao Yasugi   +6 more
openalex   +2 more sources

A novel, low-volume method for organ culture of embryonic kidneys that allows development of cortico-medullary anatomical organization.

PLoS ONE, 2010
Here, we present a novel method for culturing kidneys in low volumes of medium that offers more organotypic development compared to conventional methods. Organ culture is a powerful technique for studying renal development.
David D R Sebinger, Mathieu Unbekandt, Veronika V Ganeva, Andreas Ofenbauer, Carsten Werner, Jamie A Davies   +5 more
doaj   +2 more sources

Barrier-on-a-Chip with a Modular Architecture and Integrated Sensors for Real-Time Measurement of Biological Barrier Function

Micromachines, 2021
Biological barriers are essential for the maintenance of organ homeostasis and their dysfunction is responsible for many prevalent diseases. Advanced in vitro models of biological barriers have been developed through the combination of 3D cell culture ...
Patrícia Zoio, Sara Lopes-Ventura, Abel Oliva   +2 more
doaj   +1 more source

Prospects for fertility preservation: the ovarian organ function reconstruction techniques for oogenesis, growth and maturation in vitro

Frontiers in Physiology, 2023
Today, fertility preservation is receiving more attention than ever. Cryopreservation, which preserves ovarian tissue to preserve fertility in young women and reduce the risk of infertility, is currently the most widely practiced.
Bai Hu, Bai Hu, Renjie Wang, Renjie Wang, Di Wu, Di Wu, Rui Long, Rui Long, Jinghan Ruan, Jinghan Ruan, Lei Jin, Ding Ma, Ding Ma, Chaoyang Sun, Chaoyang Sun, Shujie Liao, Shujie Liao   +16 more
doaj   +1 more source