Results 1 to 10 of about 294,485 (187)
Development of an Ex Vivo Organ Culture Technique to Evaluate Probiotic Utilization in IBD [PDF]
The consistent technical and conceptual progress in the study of the microbiota has led novel impulse to the research for therapeutical application of probiotic bacteria in human pathologies, such as inflammatory bowel disease (IBD). Considering the heterogenous results of probiotics in clinical studies, the model of translational medicine may lead to ...
Cristiano Pagnini+3 more
core +7 more sources
Experimental liver models: From cell culture techniques to microfluidic organs‐on‐chip [PDF]
AbstractThe liver is one of the most studied organs of the human body owing to its central role in xenobiotic and drug metabolism. In recent decades, extensive research has aimed at developing in vitro liver models able to mimic liver functions to study pathophysiological clues in high‐throughput and reproducible environments.
Michela Anna Polidoro+4 more
openalex +4 more sources
Biological Effects of Clinically Relevant CoCr Nanoparticles in the Dura Mater: An Organ Culture Study [PDF]
Medical interventions for the treatment of spinal disc degeneration include total disc replacement and fusion devices. There are, however, concerns regarding the generation of wear particles by these devices, the majority of which are in the nanometre ...
Iraklis Papageorgiou+5 more
doaj +4 more sources
Is It Time to Start Transitioning From 2D to 3D Cell Culture?
Cell culture is an important and necessary process in drug discovery, cancer research, as well as stem cell study. Most cells are currently cultured using two-dimensional (2D) methods but new and improved methods that implement three-dimensional (3D ...
Caleb Jensen+5 more
doaj +3 more sources
An organ culture technique for maintaining the pulp tissue of intact human teeth
The classic organ culture method of Strangeways and Fell with all its subsequent modifications, which in fact comprise all existing organ culture techniques, strictly limits the size of explants which can be grown. Utilizing a new procedure which consists of perfusing the tissue with nutrient through small needles placed within the tissue mass, this ...
John P. DeVincenzo
openalex +5 more sources
Advances in the Biofabrication of 3D Skin in vitro: Healthy and Pathological Models [PDF]
The relevance for in vitro three-dimensional (3D) tissue culture of skin has been present for almost a century. From using skin biopsies in organ culture, to vascularized organotypic full-thickness reconstructed human skin equivalents, in vitro tissue ...
Matthew J. Randall+6 more
doaj +4 more sources
The technique of in vitro propagation of Arbuscular mycorrhizal fungi has been developed over the past few decades and opens up areas of studying plant-fungi interactions. It is a scientific break through, especially for the study of the Arbuscular mycorrhizal fungi, since these obligate symbionts depend on host plant.
Hari Prasad Aryal
openalex +3 more sources
Organ culture of gastrointestinal mucosa—a technique for the study of the human gastrointestinal tract [PDF]
P D Howdle
openalex +4 more sources
Design and Fabrication of Organ-on-Chips: Promises and Challenges
The advent of the miniaturization approach has influenced the research trends in almost all disciplines. Bioengineering is one of the fields benefiting from the new possibilities of microfabrication techniques, especially in cell and tissue culture ...
Alireza Tajeddin, Nur Mustafaoglu
doaj +1 more source
The applicability of the immunoperoxidase (IP) technique in unfixed-fresh tracheal organ cultures (TOCs) was investigated for rapid detection of infectious bronchitis virus (IBV). For this purpose, TOCs prepared from one-day-old SPF chicks were inoculated with IBV M41 strain in serial dilutions.
Ayşin Şen+3 more
openalex +5 more sources