Results 131 to 140 of about 680,344 (360)

Nucleosomes indicate the in vitro radiosensitivity of irradiated bronchoepithelial and lung cancer cells [PDF]

, 2004
Nucleosomes, which are typical cell death products, are elevated in the serum of cancer patients and are known to rapidly increase during radiotherapy.
Al-Batran SE, Albrecht Bergner, Anke Mitlewski, Bepler G, Bergner A, Dorothea Nagel, Fernando Gamarra, Jutta Stief, Kerr JF, Kuroi K, Petra Stieber, Rudolph M. Huber, Stefan Holdenrieder, Szumiel I, Wyllie AH   +14 more
core   +1 more source

Organoids in concert: engineering in vitro models toward enhanced fidelity

Aggregate
Organoids have emerged as a powerful platform for studying complex biological processes and diseases in vitro. However, most studies have focused on individual organoids, overlooking the inter‐organ interactions in vivo and limiting the physiological ...
Zhengkun Chen, Ryohichi Sugimura, Yu Shrike Zhang, Changshun Ruan, Chunyi Wen   +4 more
doaj   +1 more source

Designing stem cell niches for differentiation and self-renewal [PDF]

, 2018
Mesenchymal stem cells, characterized by their ability to differentiate into skeletal tissues and self-renew, hold great promise for both regenerative medicine and novel therapeutic discovery. However, their regenerative capacity is retained only when in
Dalby, Matthew J., Donnelly, Hannah, Salmeron-Sanchez, Manuel   +2 more
core   +1 more source

Enhanced Mechanical Properties of Injectable Chitosan–Guar Gum Hydrogel Reinforced with Bacterial Cellulose Nanofibers for Tissue Engineering Applications

Advanced Engineering Materials, EarlyView.
This study presents the development and characterization of injectable nanocomposite hydrogels based on N‐succinyl chitosan, oxidized guar gum, and bacterial cellulose nanofibers. Emphasizing enhanced mechanical properties and biocompatibility, the hydrogels exhibit fast gelation, improved structural integrity, and reduced swelling. Their potential for
Raimundo Nonato Fernandes Moreira Filho, Pascale Chevallier, Silvia Rodriguez Fernandez, Maud Viallon, Matheus Xavier de Oliveira, Ana Lorena de Brito Soares, Diego Mantovani, Judith Pessoa de Andrade Feitosa, Rodrigo Silveira Vieira   +8 more
wiley   +1 more source

Dissociated Neuronal Cultures as Model Systems for Self-Organized Prediction [PDF]

arXiv
Dissociated neuronal cultures provide a simplified yet effective model system for investigating self-organized prediction and information processing in neural networks. This review consolidates current research demonstrating that these in vitro networks display fundamental computational capabilities, including predictive coding, adaptive learning, goal-
arxiv  

Paul Alsberg (1883-1965) et le transfert adaptatif du biologique au technique : un précurseur de la "cultural niche construction" ? [PDF]

arXiv, 2008
We propose, in this paper, both a presentation and a discussion of Paul Alsberg's thesis on the supposed specificity principle of human evolution. The author maintains a difference of nature between Man and Animal relying on an opposition between "body-adaptation" - that of the Animal - and "extrabodily-adaptation" - that of Man in which the means of ...
arxiv  

Application of efficient and specific gene transfer systems and organ culture techniques for the elucidation of mechanisms of epithelial– mesenchymal interaction in the developing gut [PDF]

, 2000
Kimiko Fukuda, Nobuyuki Sakamoto, Tomohiro Narita, K. Saitoh, Takashi Kameda, Hideo Iba, Sadao Yasugi   +6 more
openalex   +1 more source

Scalable Manufacturing of Radiation‐Tolerant Potentiometric Electrodes: A Systematic Transition from Laboratory to Semiautomated Fabrication

Advanced Engineering Materials, EarlyView.
Laboratory protocols for producing thin‐film pH electrodes for sterilized single‐use technologies have been successfully developed into a semiautomated workflow, with higher throughput and precision of membrane thickness. Accuracies are within 0.05 pH units versus ground truth, and uncertainty analysis reveals the largest sources of error to be derived
Bingyuan Zhao, Aiganym Yermembetova, Benson Kunhung Tsai, Jialong Huang, Alexander Wei   +4 more
wiley   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht, Majd Machour, Inbal Michael, Maria Bulatova, Janette Zavin, Shulamit Levenberg   +5 more
wiley   +1 more source

Towards Measuring and Modeling "Culture" in LLMs: A Survey [PDF]

arXiv
We present a survey of more than 90 recent papers that aim to study cultural representation and inclusion in large language models (LLMs). We observe that none of the studies explicitly define "culture, which is a complex, multifaceted concept; instead, they probe the models on some specially designed datasets which represent certain aspects of ...
arxiv