Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research. [PDF]
Zwi-Dantsis L+5 more
europepmc +1 more source
Integration of Bioengineered Tools in Assisted Reproductive Technologies
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak+3 more
wiley +1 more source
Organ culture: the method of choice for preservation of human donor corneas
L. Pels
semanticscholar +1 more source
Developments and Applications of Liver-on-a-Chip Technology-Current Status and Future Prospects. [PDF]
Mugaanyi J+5 more
europepmc +1 more source
Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja+6 more
wiley +1 more source
Three-dimensional (3D) bioprinted co-culture models: a new paradigm for reproducing the tumor microenvironment and precision therapy. [PDF]
Du L, Lu Y, Yang H.
europepmc +1 more source
An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni+8 more
wiley +1 more source
Cryopreservation of human lung tissue for 3D ex vivo analysis. [PDF]
Diodati NG, Qu G, Mehrad B, Schaller MA.
europepmc +1 more source
Primary Layer for Universal Sensing (PLUS), a universal coating for bioprobe immobilization across diverse substrates, is introduced. Unlike conventional methods, PLUS is directly grown from dopamine and avidin, creating a roughened surface with abundant biotin‐binding sites.
Nayoung Son+5 more
wiley +1 more source
Unveiling tissue-specific transcriptional adaptations in iPSC-derived fibroblasts via co-culture systems. [PDF]
Azad AJ+7 more
europepmc +1 more source