Results 121 to 130 of about 89,507 (301)

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Non-heart beating organ donation: old procurement strategy—new ethical problems [PDF]

, 2003
M. D. D. Bell
openalex   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

Timing of Organ Procurement From Brain-Dead Donors Associates With Short- and Long-Term Outcomes After Liver Transplantation

, 2022
Verner Eerola, Ilkka Helanterä, Fredrik Åberg, Marko Lempinen, Heikki Mäkisalo, Arno Nordin, Helena Isoniemi, Ville Sallinen   +7 more
openalex   +1 more source

SMart Nanoparticle–Hydrogel Hybrid System for Synergistic Eradication of Infection and Promotion of Wound Healing

Advanced Science, EarlyView.
The integrated system, comprising bacterial‐targeted photothermal nanoparticles (Fe2O3‐CS@RBP) and multifunctional hydrogels (PAOC‐3@BA) modules, achieves rapid wound healing within one week. This work introduces a smart therapeutic platform that integrates bacterial targeting, self‐regulating photothermal therapy, tissue adhesion, and stimulus ...
Hongping Wan, Huirong Tan, Xinghong Zhao
wiley   +1 more source

The Specialized Donor Care Facility Model Improves Operating Room Efficiency

Annals of Thoracic Surgery Short Reports
Background: Organ procurement organizations coordinate organ donation through 2 distinct models of care: the conventional model, in which donors are managed at hospitals where brain death occurs, and the specialized donor care facility (SDCF) model ...
Jason M. Gauthier, MD, Yuriko Terada, MD, PhD, Tsuyoshi Takahashi, MD, PhD, Ruben G. Nava, MD, Daniel Kreisel, MD, PhD, Bryan F. Meyers, MD, MPH, Benjamin D. Kozower, MD, MPH, G. Alexander Patterson, MD, Whitney S. Brandt, MD, Gary F. Marklin, MD, Chad A. Witt, MD, Derek E. Byers, MD, PhD, Rodrigo Vazquez Guillamet, MD, Ramsey R. Hachem, MD, Varun Puri, MD, MSCI   +14 more
doaj   +1 more source

Postmortem organ procurement for transplantation. [PDF]

, 1983
Denny, DW, Starzl, TE, Van Thiel, DH
core   +1 more source

Fe‐S Protein FDX1 Triggers Tumor‐Intrinsic Innate Immunity via Mitochondrial Nucleic Acids Release to Orchestrate Ferroptosis in CCRCC

Advanced Science, EarlyView.
Restoration of the mitochondrial Fe–S protein FDX1 suppresses clear cell renal cell carcinoma by coupling ferroptosis with tumor‐intrinsic innate immune activation. FDX1 induces mitochondrial dysfunction and mtDNA/mt‐dsRNA release, activating cGAS–STING and RIG‐I/MDA5–MAVS signaling to elicit type I interferon responses, thereby promoting antigen ...
Xing Huang, Shaoqing Yu, Wenjie Wei, Wen Tao, Tianwei Cai, Lequan Wen, Jiali Ye, Chi Zhang, Huayi Feng, Senming Cao, Baojun Wang, Xin Ma, Yan Huang, Xu Zhang   +13 more
wiley   +1 more source

Mediating effects of attitude on the relationship between knowledge and willingness to organ donation among nursing students

Frontiers in Public Health
BackgroundThe current rate of organ donation in China falls significantly below the global average and the actual demand. Nursing students play a crucial role in supporting and promoting social and public welfare activities.
Xiaohang Chen, Xin Zhou, Yan Xu, Li Pan, Peizheng Li, Wenjin Liang, Lv Jin, Chunhua Zhang, Chongxiang He   +8 more
doaj   +1 more source

Mitigating Electrochemical Isolation in Ni‐Rich Layered Cathodes for Durable Solid‐State Batteries

Advanced Science, EarlyView.
Electrochemical isolation of Ni‐rich layered cathodes in sulfide solid‐state batteries is uncovered as a previously unrecognized but critical performance‐limiting pathway. This study elucidates its origin and impact and introduces a scalable mitigation strategy using oxygen‐functionalized conductive carbon.
Abhirup Bhadra, Maxime Brunisholz, Aditya Rawal, Jacob Otabil Bonsu, Tongjun Luo, Lars Thomsen, Wesley M. Dose, Dipan Kundu   +7 more
wiley   +1 more source