Results 51 to 60 of about 89,507 (301)

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Extending the Carrel system to mediate in the organ and tissue allocation processes: a first approach [PDF]

, 2002
In this paper we extend the formalization of Carrel, a virtual organization for the procurement of tissues for transplantation purposes, in order to model also the procurement of human organs for transplants. We will focus in the organ allocation process
Caballero, Francisco, Cortés García, Claudio Ulises, López-Navidad, Antonio, Padget, Julián, Vázquez Salceda, Javier   +4 more
core   +1 more source

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

Advanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin, Hanieh Mohammad Hashemi, Kimia Asadi Jozani, Anushree Chakravarty, Sonya Kouthouridis, Jessica Bonanno, Nicky Anvari, Shravanthi Rajasekar, Feng Zhang, Richard Y. Cheng, Narendra Kumar Singh, Luis Miguel Medina, Marc Durante, Yufang He, Boyang Zhang   +14 more
wiley   +1 more source

A social ecological model mapping of factors shaping health personnel’s attitudes toward organ donation: a scoping review

BMC Health Services Research
Background Although organ donation is a life-saving procedure, it faces significant challenges owing to the shortage of available organs. Health personnel play a vital role in promoting organ donation.
Huilin Zhou, Xiong Zhang, Mei Li, Rong Li, Jinhui Huang   +4 more
doaj   +1 more source

Single-Cell Transcriptome Analysis of Chronic Antibody-Mediated Rejection After Renal Transplantation

Frontiers in Immunology, 2022
Renal transplantation is currently the most effective treatment for end-stage renal disease. However, chronic antibody-mediated rejection (cABMR) remains a serious obstacle for the long-term survival of patients with renal transplantation and a problem ...
Fanhua Kong, Fanhua Kong, Shaojun Ye, Shaojun Ye, Zibiao Zhong, Zibiao Zhong, Xin Zhou, Xin Zhou, Wei Zhou, Wei Zhou, Zhongzhong Liu, Zhongzhong Liu, Jianan Lan, Jianan Lan, Yan Xiong, Yan Xiong, Qifa Ye, Qifa Ye, Qifa Ye   +18 more
doaj   +1 more source

The economic implications of HLA matching in cadaveric renal transplantation. [PDF]

, 1999
Background: The potential economic effects of the allocation of cadaveric kidneys on the basis of tissue-matching criteria are controversial. We analyzed the economic costs associated with the transplantation of cadaveric kidneys with various numbers of ...
Brennan, Daniel C, Cohen, David S, Hollenbeak, Christopher S, Howard, Todd K, Lowell, Jeffrey A, Mohanakumar, T, Schnitzler, Mark A, Singer, Gary G, Tesi, Raymond J, Woodward, Robert   +9 more
core   +2 more sources

Electro‐Stimulated Graphene‐Polymer Nanocomposites Enable Wearable Patches With Feedback‐Controlled Drug Release

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Stimuli‐responsive nanomaterials capable of spatiotemporal control over drug release are of nanocomposite patch (“e‐Medi‐Patch”) engineered from biodegradable polycaprolactone (PCL), graphene nanoplatelets, and a redox‐active therapeutic, niclosamide. The hierarchical composite integrates π‐π interactions between aromatic drug molecules
Santosh K. Misra, Ketan Dighe, Pranay Saha, Teresa Aditya, Muhammad S. Khan, Maha Alafeef, Parikshit Moitra, Dipanjan Pan   +7 more
wiley   +1 more source

Biofilm‐Antagonist Ginger‐Based 3D‐Printable Photoresins for Complex Implant Designs Exhibiting Advanced Multifunctional Biomedical Applications

Advanced Materials, EarlyView.
This work offers unique Ginger‐based 3D‐printable resins that can print customizable high‐resolution complex designs. The customizable printing backbone of Zingerol prints also mimics various human bones' strength. Acquisition of in‐vivo biocompatibility in rat model with no severe inflammatory response, along with in‐vitro antioxidant and ex‐vivo anti‐
Simran Jindal, Majd Bisharat, Bassma Khamaisi, Krishanu Ghosal, Eid Nassar‐Marjiya, Qi Wu, Shadi Daoud, Idan Redenski, Samer Srouji, Shady Farah   +9 more
wiley   +1 more source

Australian perioperative nurses’ attitudes, levels of knowledge, education and support needs related to organ donation and procurement surgery: A national survey

Journal of Perioperative Nursing, 2019
Objectives: The aim of this study was to examine Australian perioperative nurses’ self-reported knowledge, attitudes, levels of education and support in relation to their participation in organ donation and procurement surgery.
Zaneta Smith, Cindy Woods, Jackie Lea, Kim Usher   +3 more
doaj   +1 more source

Molecular Surface Engineering of Sulfide Electrolytes with Enhanced Humidity Tolerance for Robust Lithium Metal All‐Solid‐State Batteries

Advanced Materials, EarlyView.
It is demonstrated that the electrochemical, interfacial, and humidity stability of halide‐doped sulfide electrolytes (LPSClBr) is significantly enhanced by an organic surface coating using octadecyl phosphonic acid (OPA) and its lithiated form (Li‐OPA). This single‐step strategy enables robust interfacial protection, supports lithium metal anodes, and
Laras Fadillah, Leonie Braks, Jihoon Oh, Mingliang Liu, Hanna Türk, Davide Tisi, Mounir Mensi, Michele Ceriotti, Jang Wook Choi, Ali Coskun   +9 more
wiley   +1 more source