Results 71 to 80 of about 89,507 (301)

Benchmarking Organic Photodiodes at the Noise Floor

Advanced Optical Materials, EarlyView.
A precise measurement framework based on a calibrated, ultra‐low‐noise automated setup with open‐source Python scripts enables accurate benchmarking of photodiodes. The unique combination of time‐dependent current measurement under dark conditions, followed by continuous‐wave faint illumination, facilitates reliable extraction of photocurrent near ...
Siddhartha Saggar, Giedrius Puidokas, Caroline Murawski   +2 more
wiley   +1 more source

Mild hypothermia attenuates hepatic ischemia-reperfusion injury by regulating FoxO1/PPARα pathway

Scientific Reports
Hepatic ischemia-reperfusion injury (IRI) is a common complication of hepatectomy and liver transplantation. As far as we know, mild hypothermia (MH) is an effective measure to alleviate liver IRI.
Zhongshan Lu, Hao Chen, Anxiong Liu, Shufang Na, Wei Wang, Zibiao Zhong, Qifa Ye   +6 more
doaj   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Designing a Compensated–Kidney Donation System [PDF]

, 2014
Osteochondral lesions of the talus (OLTs) are the third most common type of osteochondral lesion and can cause pain and instability of the ankle joint. Episurf Medical AB is a medical technology company that develops individualized implants for patients ...
Beard, T. Randolph, Leitzel, Jim
core   +2 more sources

Survey the Frequency of Organ Donation and Related Factors in Patients with Consciousness Level below 5 in Hospitals of Guilan Province: An Analytical Study [PDF]

مجله دانشگاه علوم پزشکی گیلان
Background: Statistics of accidents, decreased level of consciousness and occurrence of brain death in Iran are high. In this regard, the use of brain death cases in organ transplantation has been carried out in Iran for a long time and several factors ...
Ali Monfared, Siamak Rimaz, Saeid Anvari, Latif Panahi, Samaneh Ghazanfar Tehran, Somaye Pouy, Keyvan Abdi, Arezo Khiali, Morteza Rahbar-Taramsari, Saman Maroufizadeh   +9 more
doaj  

Exploring grief and acceptance: Experiences and needs of family members of deceased organ donors

SAGE Open Medicine
Objective: Before considering organ donation, family members must come to terms with the fact that their loved one is brain dead and that organ donation is a meaningful path forward. This acceptance enables their consent to organ donation following brain
Marzieh Latifi, Elahe Pourhosein, Habib Rahban, Fatemeh Estebsari, Maryam Pourhossein, Sanaz Dehghani   +5 more
doaj   +1 more source

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

Advanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo, Shuai He, Shirui Chen, Dongmei Ye, Shibo Zhang, Di Liu, Dawei Zou, Linhe Wang, Huadi Chen, Jinghong Xu, Huanjie Liu, Ruiting Liu, Xi Tan, Yitong Wang, Jiayi Zeng, Runbing Mo, Yuexin Li, Yuyi Zhang, Tanyiyang Ruan, Tielong Wang, Zehua Jia, Yu Jia, Tongdi Fang, Yimou Lin, Xiaorui Liu, Yunhua Tang, Maogen Chen, Qiang Zhao, Anbin Hu, Weiqiang Ju, Yi Ma, Dongping Wang, Xiaofeng Zhu, Schlegel Andrea, Yuan Zhai, Kwan Man, Tullius G. Stefan, Yifang Gao, Jinxin Bei, Xiaoshun He, Zhiyong Guo   +40 more
wiley   +1 more source

Deceased Donors With HIV in the Era of the HOPE Act: Referrals and Procurement

Transplantation Direct
Background. The HIV Organ Policy Equity Act legalizes organ procurement from donors with HIV (HIV D+). A prior survey of Organ Procurement Organizations (OPOs) estimated >2000 HIV D+ referrals/year; however, only 30–35 HIV D+/year have had organs ...
Tao Liang, MSPH, Jordan H. Salas, BS, MCR, Mary G. Bowring, MPH, Oyinkan Kusemiju, MPH, Brittany Barnaba, MS, Matthew Wingler, CPTC, Deborah McRann, MBA, Alghidak Salama, MD, MPA, R. Patrick Wood, MD, Allan Massie, PhD, William Werbel, MD, PhD, Aaron A. R. Tobian, MD, PhD, Dorry L. Segev, MD, PhD, Christine M. Durand, MD   +13 more
doaj   +1 more source

Presumed consent for organ preservation in uncontrolled donation after cardiac death in the United States: a public policy with serious consequences

Philosophy, Ethics, and Humanities in Medicine, 2009
Organ donation after cessation of circulation and respiration, both controlled and uncontrolled, has been proposed by the Institute of Medicine as a way to increase opportunities for organ procurement.
Rady Mohamed Y, Verheijde Joseph L, McGregor Joan   +2 more
doaj   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source