Results 41 to 50 of about 1,559,469 (190)

The temporal requirements for insulin signaling during development in Drosophila. [PDF]

open access: yesPLoS Biology, 2005
Recent studies have indicated that the insulin-signaling pathway controls body and organ size in Drosophila, and most metazoans, by signaling nutritional conditions to the growing organs. The temporal requirements for insulin signaling during development
Alexander W Shingleton   +3 more
doaj   +2 more sources

Spectrin regulates Hippo signaling by modulating cortical actomyosin activity

open access: yeseLife, 2015
The Hippo pathway controls tissue growth through a core kinase cascade that impinges on the transcription of growth-regulatory genes. Understanding how this pathway is regulated in development remains a major challenge.
Hua Deng   +5 more
doaj   +1 more source

Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish

open access: yeseLife, 2015
During development, proliferation must be tightly controlled for organs to reach their appropriate size. While the Hippo signaling pathway plays a major role in organ growth control, how it senses and responds to increased cell density is still unclear ...
Sobhika Agarwala   +9 more
doaj   +1 more source

Open and / or laparoscopic surgical treatment of liver hydatic cysts [PDF]

open access: yes, 2018
Hydatid disease is a severe parasitic disease with a widely ranging distribution. In the human being the liver is the most frequent organ affected. 1 The treatment should be individualized to the morphology, size, number and location of the cysts, that ...
Al Karowda‘a E. A.   +9 more
core   +1 more source

Ultrasonographic parameters of the liver, spleen and kidney in a healthy paediatric population in Bosnia and Herzegovina: a prospective study

open access: yesMedicinski Glasnik
Aim To determine the normative range of ultrasound dimensions for the liver, spleen and kidneys in healthy children according to gender, age, body measurements, body surface area (BSA), and the influence of ethnicity on organ size.Methods The prospective
Nina Мekić   +7 more
doaj   +1 more source

The hippo signaling pathway: implications for heart regeneration and disease [PDF]

open access: yes, 2014
Control of cell number and organ size is critical for appropriate development and tissue homeostasis. Studies in both Drosophila and mammals have established the Hippo signaling pathway as an important modulator of organ size and tumorigenesis.
Dominic P Del Re
core   +1 more source

The biology of organ size determination [PDF]

open access: yesDiabetes, Obesity and Metabolism, 2008
The mechanisms that control the size of cells, organs, and organisms have long interested biologists, and are also important in malignant progression. Despite this, basic features of in vivo growth control – the level at which regulation is exerted and the degree to which size is controlled ...
openaire   +2 more sources

Evidence of strong stabilizing effects on the evolution of boreoeutherian (Mammalia) dental proportions. [PDF]

open access: yes, 2019
The dentition is an extremely important organ in mammals with variation in timing and sequence of eruption, crown morphology, and tooth size enabling a range of behavioral, dietary, and functional adaptations across the class.
Archibald J. D.   +26 more
core   +6 more sources

Ontogenic Caste Differences in the Van der Vecht Organ of Primitively Eusocial Neotropical Paper Wasps. [PDF]

open access: yesPLoS ONE, 2016
Recent studies have reported incipient morphological caste dimorphism in the Van der Vecht organ size of some temperate Polistes paper wasps. Whether species other than the temperate ones show a similar pattern remains elusive. Here, we have studied some
André Rodrigues de Souza   +5 more
doaj   +1 more source

Heat Exchanger Sizing for Organic Rankine Cycle [PDF]

open access: yesEnergies, 2020
Approximately 45% of power generated by conventional power systems is wasted due to power conversion process limitations. Waste heat recovery can be achieved in an Organic Rankine Cycle (ORC) by converting low temperature waste heat into useful energy, at relatively low-pressure operating conditions.
James Bull   +2 more
openaire   +3 more sources

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