Results 111 to 120 of about 465,843 (360)

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi   +13 more
wiley   +1 more source

SF3B4 regulates proliferation and apoptosis in hepatocellular carcinoma via alternative splicing and interaction with TRIM28 and SETD5

open access: yesJournal of Translational Medicine
Background SF3B4 encodes a core subunit of the U2-type spliceosome and is implicated in abnormal cell growth and tumorigenesis. However, its role in regulating gene expression and alternative splicing in hepatocellular carcinoma (HCC) remains ...
HanFei Huang   +9 more
doaj   +1 more source

Personalized Donor-Recipient Matching for Organ Transplantation [PDF]

open access: yesarXiv, 2016
Organ transplants can improve the life expectancy and quality of life for the recipient but carries the risk of serious post-operative complications, such as septic shock and organ rejection. The probability of a successful transplant depends in a very subtle fashion on compatibility between the donor and the recipient but current medical practice is ...
arxiv  

Hepatic artery pseudoaneurysm ligation after orthotopic liver transplantation-a report of 7 cases [PDF]

open access: yes, 1992
Pseudoaneurysm (PA) is a rare but life-threatening complication of liver transplantation. The authors present their experience on 7 patients treated by ligation of a post-OLT PA.
Gordon, R   +7 more
core   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

open access: yesAdvanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell   +5 more
wiley   +1 more source

Low proportion of follicular regulatory T cell in renal transplant patients with chronic antibody-mediated rejection

open access: yesScientific Reports, 2017
Follicular regulatory T (Tfr) cell can effectively regulate humoral immunity, but its function and mechanism in antibody-mediated rejection (AMR) after organ transplantation remains unclear.
Wen Chen   +8 more
doaj   +1 more source

Using deceased-donor kidneys to initiate chains of living donor kidney paired donations: algorithms and experimentation [PDF]

open access: yesarXiv, 2018
We design a flexible algorithm that exploits deceased donor kidneys to initiate chains of living donor kidney paired donations, combining deceased and living donor allocation mechanisms to improve the quantity and quality of kidney transplants. The advantages of this approach have been measured using retrospective data on the pool of donor/recipient ...
arxiv  

The Role of Organ Transplantation in Pediatrics [PDF]

open access: green, 1966
Thomas E. Starzl   +4 more
openalex   +1 more source

Bioprinting Perfusable and Vascularized Skeletal Muscle Flaps for the Treatment of Volumetric Muscle Loss

open access: yesAdvanced Healthcare Materials, EarlyView.
Volumetric muscle loss (VML) due to trauma or surgery, often leads to physical impairments. Traditional treatments rely on autologous flaps, limited by muscle availability often leading to donor site morbidity. This study presents multimodal bioprinting as an innovative approach for fabricating vascularized muscle flaps with 3D‐printed macrovessels ...
Eliana O. Fischer   +8 more
wiley   +1 more source

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