Results 121 to 130 of about 457,713 (360)

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Exploring pharmacodynamics of immunosuppresive agents in transplantation [PDF]

, 2013
Supported by advancements in technology, surgical techniques and immunosuppressive drugs, solid organ transplantation has become the preferred solution to end stage organ failure.
Vafadari, R. (Ramin)
core   +1 more source

Invasive Aspergillosis in Solid Organ Transplant Recipients [PDF]

, 2009
N. Singh, Shahid Husain
openalex   +1 more source

Electrochemical Biosensor for Rapid Detection of Acute Rejection in Kidney Transplants

Advanced Healthcare Materials, EarlyView.
A low‐cost, rapid electrochemical immunosensor coated with a novel antifouling nanocomposite enables single‐step, dual‐biomarker profiling directly from unprocessed urine. Application in a clinical study shows accurate discrimination of acute rejection in kidney transplants from other acute kidney injuries via machine learning.
Rohit Gupta, Nikolaos Salaris, Ashish Kalkal, Fernando Yuen Chang, Maryam Javed, Azhar Ali Khan, Priya Mandal, Stavroula Balabani, Reza Motallebzadeh, Manish K. Tiwari   +9 more
wiley   +1 more source

PB2200: CLONAL HEMATOPOIESIS AT THE CROSSROADS OF INFLAMMATORY BOWEL DISEASES AND HEMATOLOGICAL MALIGNANCIES: A BIOLOGICAL LINK?

HemaSphere, 2022
C. Cumbo, F. Tarantini, A. Zagaria, L. Anelli, C. F. Minervini, N. Coccaro, G. Tota, L. Impera, E. Parciante, M. R. Conserva, I. Redavid, P. Carluccio, M. Delia, A. Giordano, C. Longo, T. Perrone, A. Russo Rossi, G. Specchia, P. Musto, F. Albano   +19 more
doaj   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

MDSC suppresses T cell antitumor immunity in CAC via GPNMB in a MyD88‐dependent manner

Cancer Medicine
Background Myeloid‐derived suppressor cells (MDSCs) played an essential role in tumor microenvironment to suppress host antitumor immunity and help cancer cells escape immune surveillance. However, the molecular mechanism behind tumor evasion mediated by
Bo Wang, Lu Wang, Runshi Shang, Lin Xie
doaj   +1 more source

Analysis of liver transplant outcomes for United Network for Organ Sharing recipients 60 years old or older identifies multiple model for end-stage liver disease-independent prognostic factors [PDF]

, 2010
Thomas A. Aloia, Richard J. Knight, A. Osama Gaber, R. Mark Ghobrial, John A. Goss   +4 more
openalex   +1 more source

Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology

Advanced Healthcare Materials, EarlyView.
In vitro breast cancer models that closely mimic the complex biological and cellular interactions within the tumor microenvironment hold strong promise for enhancing our understanding of tumor progression, immune system behavior, and resistance to therapies, which are essential for developing personalized cancer treatments. Abstract Engineered in vitro
Wonwoo Jeong, Sang Jin Lee
wiley   +1 more source

Clinical outcomes of kidney transplantation from expanded-criteria donors and KDPI>85% kidneys in deceased Chinese donors

BMC Nephrology
Background Kidney transplantation is the optimal treatment for end-stage renal disease; however, the limited availability of donor kidneys hinders the advancement of this procedure.
Kankan Shui, Hedong Zhang, Tengfang Li, Jianfei Hou, Gongbin Lan, Fenghua Peng, Shaojie Yu, Xubiao Xie, Helong Dai, Longkai Peng   +9 more
doaj   +1 more source