Results 231 to 240 of about 457,713 (360)

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Chimerism and immunological tolerance in solid organ transplantation. [PDF]

Semin Immunopathol
Ohm B, Giannou AD, Harriman D, Oh J, Jungraithmayr W, Zazara DE.   +5 more
europepmc   +1 more source

Quadruple-drug induction therapy in highly sensitized patients [PDF]

, 1988
Abendroth, D., Illner, Wolf-Dieter, Land, Walter, Schleibner, S.   +3 more
core   +1 more source

Gut Microbial Genetic Variation Prolongs Host Healthy Longevity and Remodels Metabolome and Proteome in Drosophila Melanogaster

Advanced Science, EarlyView.
This study reveals that specific genetic variations in gut‐residing Saccharomyces cerevisiae significantly extend healthspan and lifespan in Drosophila melanogaster. These mutants rejuvenate aged intestinal metabolism, upregulate mitochondrial proteins, and enhance energy pathways.
Liying Wang, Ziling Yang, Yulu Pang, Xinyue Wu, Xinrong Zhang, Tao Zhu, Xiaoyue Ding, Wei Liu, Yuan Zhou, Pengcheng Zhang, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Systemic Mastocytosis with Associated Chronic Lymphocytic Leukemia: A Matter of Diseases or Prognostic Factors?

Turkish Journal of Hematology, 2017
Antonella Zagaria, Luisa Anelli, Nicoletta Coccaro, Giuseppina Tota, Claudia Brunetti, Angela Minervini, Paola Casieri, Luciana Impera, Crescenzio Francesco Minervini, Annamaria Giordano, Paola Orsini, Cosimo Cumbo, Giorgina Specchia, Francesco Albano   +13 more
doaj   +1 more source

Influence and Role of Regulatory B Cells in Organ Transplantation: The State of the Art, Prospects, and Emerging Insights. [PDF]

Antibodies (Basel)
Fernández-González M, Llorente S, Galián JA, Botella C, González-López R, Alegría MJ, Hita A, Moya-Quiles MR, Martinez-Banaclocha H, Muro-Pérez M, Muro J, Minguela A, Legaz I, Muro M.   +13 more
europepmc   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source

Role of autophagy in rejection after solid organ transplantation: A systematic review of the literature. [PDF]

World J Transplant
Jiang SM, Li XJ, Wang ZL, Chen ZW, Liu ZL, Li Q, Chen XL.   +6 more
europepmc   +1 more source

Interferon‐Driven Biomarkers and Synergistic Therapy for PRMT5 Inhibition in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer exhibits variable sensitivity to PRMT5 inhibition. Basal interferon signaling is identified as a key biomarker of response. PARP inhibition with olaparib induces IFN signaling, sensitizing resistant TNBC cells to PRMT5 inhibitors.
Ziwen Zhang, Sheyu Zhang, Lu Guo, Yichun Pan, Juan Huang, Yishuai Ji, Jiaqi Tao, Yong Wei, Xiaojia Wang, Qin Wu   +9 more
wiley   +1 more source

Ethics and Algorithms to Navigate AI's Emerging Role in Organ Transplantation. [PDF]

J Clin Med
Salybekov AA, Yerkos A, Sedlmayr M, Wolfien M.   +3 more
europepmc   +1 more source