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Organ Donation and Transplantation
2012This article examines key ethical issues involved in organ donation and transplantation. A brief initial overview is provided of general ethical issues that arise in relation to deceased and living organ donation, as well as xenotransplantation. Thereafter, the role played by the gift of life metaphor in underpinning the system of organ donation as ...
Farrell, A, Quigley, M
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Gout and Organ Transplantation
Current Rheumatology Reports, 2012Acute and chronic gout are common complications following organ transplantation. Risk factors include those shared with the general population (eg, diuretic use) and transplant-specific risk factors (eg, cyclosporine). Clinical features of gout are similar to those seen in the general population, although tophi may be more common.
Lisa K, Stamp, Peter T, Chapman
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Angiogenesis and organ transplantation
Folia Microbiologica, 2004Angiogenesis is a vessel development process that maintains the vascular supply for organ function. Regulation of angiogenesis is provided by positive factors, such as vascular endothelial or basic fibroblast growth factors, and negative factors, such as thrombospondin and macrophage-derived inflammatory cytokines. While the role of angiogenesis in the
J, Rajnoch, O, Viklický
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Cyclosporin A in organ transplantation
Medical Journal of Australia, 1986Cyclosporin A is a novel, powerful immunosuppressive agent. It is a cyclic polypeptide and is one of several metabolites of a number of soil fungi. Its main effect is directed against the helper T lymphocyte. Thus, cyclosporin A represents the first of a new generation of immunosuppressive agents that are capable of selective rather than broad spectrum
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Immunosuppressants in Organ Transplantation
2019The goal of immunosuppressive therapy post-transplantation in pediatric renal transplant recipients is to prevent acute and chronic rejection while minimizing drug side effects. Most therapies alter immune response mechanisms but are not immunologically specific, and a careful balance is required to find the dose that prevents rejection of the graft ...
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Immunosuppression in Organ Transplantation
New England Journal of Medicine, 1990The search for effective and safe methods of suppressing the immune response has been evolving over four decades. Progress has been marked by many disappointments and a few forward leaps.
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Enzyme Therapeutic for Ischemia and Reperfusion Injury in Organ Transplantation
Advanced Materials, 2022Chen Zhang, Zhihua Gan, Chaoyong Liu
exaly