Results 261 to 270 of about 457,713 (360)

Hepatic KLF9 Deficiency Inhibits Dehydroepiandrosterone (DHEA)‐Induced Polycystic Ovary Syndrome via Liver‐Ovary Axis

Advanced Science, EarlyView.
The study shows that liver is a previously unrecognized extraovarian organ that plays a key role about androgen homeostasis in the development of DHEA‐induced PCOS. DHEA is the most common precursor of active androgen, such as DHT, and KLF9 is required for the conversion of DHEA to DHT and hepatic KLF9 might be a potential therapeutic target for PCOS ...
Jianli Song, Zhaoqing Guan, Guiyi Ji, Jing Wang, Xiurui Yan, Yujie Zhang, Yinliang Zhang, Chunfang Ha, Rong Hu, Yongsheng Chang, Yaolin Zhang, Heng Fan   +11 more
wiley   +1 more source

A population-based analysis of immunosuppression therapy after organ transplantation. [PDF]

BMC Health Serv Res
Hörbrand F, Stahn D, Killian P, Weichenberger L, Böhler D, Bramlage P.   +5 more
europepmc   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

Moral and Ethical Reflections on Human Organ Transplantation [PDF]

, 1964
Murray, Joseph E.
core   +1 more source

Mesenchymal Stem Cell‐Derived Extracellular Vesicles Modulate the Course of Peritoneal Inflammation Through Metabolic and Epigenetic Regulation

Advanced Science, EarlyView.
MSC‐EVs alleviate peritoneal inflammation and fibrogenesis by disrupting the H3K18la‐CCL2 axis and crosstalk between mesothelial cells and Ly6c2⁺ macrophages. Model cartoons are constructed using the Biorender website (https://www.biorender.com/), and a usage license is obtained. Abstract Peritoneal dialysis (PD), as a renal replacement therapy, relies
Qiang Huang, Yuxiang Sun, Pengpeng Kuang, Juan Sun, Dandan Guo, Long Peng, Hu Zhou, Qinrong Song, Zhihao Huo, Canming Li, Janusz Witowski, Zhaoyong Hu, Hui Peng   +12 more
wiley   +1 more source

Obesity treatment as a bridge to solid organ transplantation: A comparison of bariatric surgery to medical therapy. [PDF]

Obes Pillars
Roddy KL, Greenwald MR, Hollman N, Dorand MF, Richards JR.   +4 more
europepmc   +1 more source

Chimerism after whole organ transplantation: an explanation of renal and other organ acceptance [PDF]

, 1997
Demetris, AJ, Murase, N, Rao, AS, Starzl, TE, Thomson, AW, Trucco, M   +5 more
core  

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

Advanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang   +8 more
wiley   +1 more source

A narrative review on the psychosocial domains of the impact of organ transplantation. [PDF]

Discov Ment Health
Aderinto N, Olatunji G, Kokori E, Ogieuhi IJ, Moradeyo A, Woldehana NA, Lawal ZD, Adetunji B, Assi G, Nazar MW, Adebayo YA.   +10 more
europepmc   +1 more source

The flaws of immunosuppression in organ transplantation today [PDF]

, 1975
Starzl, TE
core